Category Archives: Chronic Disease

Microbiome Restore Protocol

Dr Andrew Orr’s Microbiome Restore Protocol

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The Purpose Of The Microbiome Restore

Many inflammatory health conditions can be linked to compromised microbiome and poor gut health. There is now good research and evidence to show the importance of microbiome restore.

Within these poor health states, there is often an overgrowth of “bad” bacteria within your gut. This is a crucial part of treatment for these ailments to restore the microbiome and replenish the “good” bacteria. Ressearch has also linked poor gut health to many mental health conditions.

There are many things that impact the microbiome. Refined food commonly found in the typical Western diet, stress, alcohol, drugs, medications, hormones and many other things fosters the growth of this “bad” bacteria, causing inflammation and what we know as ‘dysbiosis’.

Dr Orr’s Microbiome Restore Protocol aims to reduce the intake of these refined foods and others things that impact the microbiome, and and instead foster the growth of “good” bacteria.

The Eating Plan

This eating plan is based on Dr Andrew Orr’s Primal Ancestral Clean Eating (PACE) diet.  It does allow quite a range of foods, so you shouldn’t have any trouble eating at home, or out anywhere. It is important to note that this is not a “diet.” This is simply the way we are supposed to eat.

2 Phase Microbiome Restore Protocol

Prior to starting the microbiome restore will also need to complete some health questionnaires and have a half hour consultation with Dr Andrew. The health questionnaire need to be fully completed and sent back prior to your consultation. All the relevant information will be supplied to you when you enquire, or book your consultation.

Alongside the PACE diet, this Microbiome Restore Protocol also involves supplementation that is set out in two phases. Both phases need to be completed in order to achieve working results.

Please note that the supplements prescribed as part of the microbiome restore protocol are practitioner only prescribed supplements which will require a consultation before they can be prescribed.

Phase 1 – Removal of Bad Bacteria & Gut Lining Repair

The first phase aims to restore the gut lining, remove bad bacteria and microbials, and create an environment in which good bacteria can thrive. Phase 1 will not need to be repeated (unless you wish you repeat the process in the future). It lasts for approximately 4 weeks, or until all of the products are finished. After that, you move on to phase 2 which then is also the maintenance phase.

Phase 2 – Replenishing the Microbiome & Good Gut Bacteria

After removing the bad bacteria, repairing the gut lining, and laying down a foundation for the good bacteria to grow, you will need to recolonise your gut with good bacteria. Strain specific bacteria are used and it will depending on the individual which probiotic strains are used.

Phase 2 aims to replenish the good gut bacteria through the use of Pre and Probiotics. This phase will be ongoing and used as maintenance for your condition. It is extremely important to continue your intake of Pre and Probiotics to ensure proper colonisation of good bacteria and restore on the microbiome.

Important Things To Note

It is important to note that the results of doing the microbiome restore could take months to come into effect and for there to be adequate good bacteria colonisation. It is likely that if you have been recommended to take part in this protocol, that your microbiome is quite compromised due to years of consistent damage. Because of this, it will likely take quite a while to properly restore the microbiome back to equilibrium. This is done by way of continuing with your prebiotics and strain specific healthy bacteria,  to get back on track and eventually feel healthier.

As mentioned previously, many things can impact gut bacteria including stress, alcohol, diet, etc. so it is important to be mindful of this and what you expose your body to on your pathway to recovery.

A good way to think of a damaged microbiome is like any other damaged organ or bone in the body. A broken bone, torn ligament, or damaged internal organ is not likely to heal overnight. It can take months or even years of recovery, rehabilitation or medicinal therapies to get on top of it. The same applies for your digestive tract. It is no exception to the rule in regards to healing time within your body. The best results come when people are consistent in sticking to their treatment plan, and are realistic about time frames and outcomes.

Next Step Is Book Your Consultation

If you need help with restoring your microbiome for better health, then please give my clinic staff a call and find out how my Microbiome Restore Protocol may be able to assist you on the pathway to better health. There are options for online, or in person consultations. Conditions may apply to online consultations.

For further information please call +61 07 38328369, or email info@drandreworr.com.au

References

  1. Walker A, et al. Phylogeny, culturing, and metagenomics of the human gut microbiota. Trends Microbiol. 2014;22:267–74.
  2. Collado MC, et al. Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus. Lett Appl Microbiol. 2007;45(4):454-60.
  3. Leahy SC, et al. Getting better with bifidobacteria. J Appl Microbiol. 2005;98(6):1303-15.
  4. McFarland LV. Systematic review and meta-analysis of Saccharomyces boulardii in adult patients. World J Gastroenterol. 2010;16(18):2202-22.
  5. Jahn HU, et al. Immunological and trophical effects of Saccharomyces boulardii on the small intestine in healthy human volunteers. Digestion. 1996;57(2):95-104.
  6. Jahn HU, et al. Immunological and trophical effects of Saccharomyces boulardii on the small intestine in healthy human volunteers. Digestion. 1996;57(2):95-104.
  7. Dahan S, et al. Saccharomyces boulardii interferes with enterohemorrhagic Escherichia coli induced signaling pathways in T84 cells. Infect Immun. 2003;71:766-773.
  8. Hsieh H. Versalovic J. The human microbiome and probiotics: Implications for pediatrics. Curr Probl Pediatr Adolesc Health Care. 2008;38(10):309–327.
  9. Lam EK, et al. Enhancement of gastric mucosal integrity by Lactobacillus rhamnosus GG. Life Sci. 2007;80(23):2128-36.
  10. Seth A, et al. Probiotics ameliorate the hydrogen peroxide-induced epithelial barrier disruption by a PKC- and MAP kinase-dependent mechanism. Am J Physiol Gastrointest Liver Physiol. 2008;294(4):G1060-9.
  11. Gibson GR. Roberford M. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr. 1995;125:1401-1412.
  12. Fastinger ND, et al. A novel resistant maltodextrin alters gastrointestinal tolerance factors, fecal characteristics, and fecal microbiota in healthy adult humans. J Am Coll Nutr. 2008;27(2):356-66.
  13. Raninen K, et al. Dietary fiber type reflects physiological functionality: comparison of grain fiber, inulin, and polydextrose. Nutr Rev. 2011;69(1):9-21.
  14. Robison LE. Reeves S. EpiCor® and its immune effects on gut health. Embria Health Sciences, LLC. [Online]. No date. Available from: http://www.embriahealth.com/upload/pdf/EpiCor%20Science%20%20EpiCor%20and%20its%20Immune%20Effects%20on%20Gut%20Health_FINAL.pdf [Cited 16/02/13].
  15. Jensen GS, et al. Antioxidant bioavailability and rapid immune-modulating effects after consumption of a single acute dose of a high-metabolite yeast immunogen: results of a placebo-controlled double-blinded crossover pilot study. J Med Food. 2011 Sep;14(9):1002-10.
  16. Bartoli, C., Frachon, L., Barret, M., Huard-Chauveau, C., Mayjonade, B., Zanchetta, C., … & Roux, F. (2018, May 30). In situ relationships between microbiota and potential pathobiota in Arabidopsis thaliana. The ISME Journal. Retrieved from https://www.nature.com/articles/s41396-018-0152-7#article-info
  17. Berg, R. D. (1996). The indigenous gastrointestinal microflora. Trends in Microbiology, 4(11), 430-435. Retrieved from https://www.sciencedirect.com/science/article/pii/0966842X96100573
  18. Carpenter, S. (2012, September). That gut feeling. Monitor on Psychology, 43(8), 50. Retrieved from http://www.apa.org/monitor/2012/09/gut-feeling.aspx
  19. Clapp, M., Aurora, N., Herrera, L., Bhatia, M., Wilen, E., & Wakefield, S. (2017, September 15). Gut microbiota’s effect on mental health: The gut-brain axis. Clinics and Practice, 7(4), 987. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641835/
  20. NIH Human Microbiome Project. (n.d.). Retrieved from https://hmpdacc.org/
  21. Shepherd, E. S., DeLoache, W. C., Pruss, K. M., Whitaker, W. R., & Sonnenburg, J. L. (2018, May 9). An exclusive metabolic niche enables strain engraftment in the gut microbiota [abstract]. Nature, 557, 434-438. Retrieved from https://www.nature.com/articles/s41586-018-0092-4
  22. The Human Microbiome Project Consortium. (2012, 14 June). Structure, function and diversity of the healthy human microbiome. Nature, 486, 207-214. Retrieved from https://www.nature.com/articles/nature11234
  23. Ursell, L. K., Metcalf, L., K., Wegener Parfry, L., Knight, R. (2012, August). Defining the human microbiome. Nutrition Reviews, 70(Suppl 1), S38-S44. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426293/
Medications affecting the microbiome

Many Medications Significantly Affects The Microbiome

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New research is emerging to show that many medications significantly affect the microbiome and lead to long term health implications through disruption of healthy gut bacteria.

As mention already in my previous post about the importance of proper restoring the microbiome for optimum health, many medications and hormones actually have a toxic affect on the microbiome and can cause dysbiosis. It is crucial to for all of us to understand the consequences of medication use in the gut microbiome. I’ll talk about this in my next post.

A new study has found that many common drugs — including those that treat diabetes, digestive problems, bacterial infections, and even depression — could actually predispose people to certain types of infection by affecting the balance of their gut microbiome.

New findings

A new study from the University Medical Centre Groningen and the Maastricht University Medical Centre, both in the Netherlands, has found evidence to suggest that many common drugs — from antibiotics to antidepressants — have a significant impact on the gut microbiome. They can even disrupt the delicate balance of bacterial populations.

The researchers compared the results of people who took prescription drugs with those of people who did not. They also looked at the effects of individual medications versus combinations of drugs.

They found that 18 common drug categories have a significant impact on the bacterial composition of the gut microbiome, which could lead to serious health issues. These health issues included intestinal infections, obesity, gastrointestinal conditions and various conditions linked to gut health.

Many Medications Disrupt The Microbiome

While pain medications, steroids, antidepressant and hormones (contraceptives and hormone replacement) were shown to significantly impact the bacterial balance in the microbiome, four drug categories appeared to have the strongest impact. These were:

  • Proton pump inhibitors (PPIs), which reduce the production of stomach acid
  • Metformin, which helps people manage the symptoms of type 2 diabetes
  • Antibiotics, which fight bacterial infections
  • Laxatives, which help treat constipation

The analyses revealed that people who took PPIs had more upper gastrointestinal tract dysbiotic bacteria, and that their bodies produced more fatty acid. Meanwhile, those who took metformin had higher levels of Escherichia coli, a bacteria that can cause diarrhoea and urinary tract infections. One of the reasons many stop Metformin is because of significant gastrointestinal symptoms and pain. Long term it can also damage the liver.

Antibiotics Significantly Impact The Microbiome

We have always know that antiobiotics have an major impact on the gut and microbiome, but many people are unaware that all medications have the potential to disrupt the microbiome and cause significant harm to our health long term.

When it comes to antibiotics, alarmingly Australians are amongst the highest users of antibiotics in the world with 46% of the population taking one course of antibiotics annually.

A single course of antibiotics can disrupt the gut microbiota quantity and composition for up to four years. The loss of microbial balance leads to a breakdown of endothelial barrier protection, increased intestinal permeability, and subsequent immune dysregulation.

Proper Microbiome restore needs to be done properly

As mentioned in my previous post, the good news is although a dysfunctional microbiome can come about rapidly, you can begin to restore a healthy microbiome just as quickly through strategic microbiome restore.

As I have said before, when it comes to proper microbiome restore,  it isn’t just as easy as taking any old probiotic, or a combination of probiotics. Microbiome restore requires and individualised and strain specific approach and it needs to be done in stages with antimicrobials, gut repair and prebiotics as well. Dysbiotic microbes can be hard to treat effectively because they have evolved and adapted to life inside human beings. Consequently, elimination of these organisms requires a similarly evolved and adapted approach. This is all part of the microbiome restore protocol I use with my patients.

If you would like to find out how to restore your microbiome properly, please give my friendly staff a call and find out how I may be able to assist you.

Regards

Andrew Orr

-No Stone Left Unturned

-Women’s and Men’s Health Advocate

 

Microbiome

The Importance Of Properly Restoring The Microbiome For Optimum Health

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One of the things I teach my patients is the importance of properly restoring the microbiome for optimum health and also reducing inflammation in the body.

Many people’s daily bloating, fluid retention, gastrointestinal symptoms, health issues, chronic disease states are being exacerbated by an unhealthy balance in this unique ecosystem we call the microbiome.

The problem is that many people do not really understand the importance of the microbiome, and even many healthcare professionals do not fully understand how to help with proper microbiome repair and restore.

Many people are also led to believe that by just taking probiotics, that this is enough to restore the healthy bacteria in the gut/microbiome.

I wish it was that easy, but it isn’t and this is why many people continue to have gastrointestinal issues, inflammation and chronic health issues, despite thinking that are doing the right thing for their gut health.

What is the Microbiome?

The human gastrointestinal tract (GIT) is host to an extraordinary amount of microorganisms composed of bacteria, viruses and microbes, collectively known as the microbiome. The microbiome is the name given to all of the genes inside these microbial cells.

Every human being has anywhere between 10 trillion and 100 trillion microbial cells all working together in a symbiotic relationship. This benefits both the microbes and their hosts, as long as the body is in a healthy state.

Recent scientific advances in genetics mean that humans know a lot more about the microbes in the body. There has been lot of time and money put into researching the interactions within the human body’s ecosystem and their relevance to health and disease.

The two terms ‘microbiota’ and ‘microbiome’ are often used to mean the same thing and are used interchangeably. I will explain the differences between them and how both are being used and researched in modern medicine.

You exist in a symbiotic relationship with your bacterial ecosystem, and there is a two-way relationship that makes your health inseparable from that of your microbiome and vice versa.

The benefits of a healthy microbiome/microbiota

The benefits of a healthy microbiome/microbiota, extend beyond the gut and digestive system and has a significant systemic impact on some the following:

  • Nutrient metabolism
  • Body composition (weight)
  • Cardiovascular health,
  • Chronic disease states
  • Inflammation in the body
  • Pain pathways
  • Immunity
  • Mental Health
  • Neuroendocrine function
  • Gene Expression

What is the Microbiota

The gut microbiota used to be called the microflora of the gut. The importance of the microbiota has been known for a long time, but now medical science is discovering just how important it is, and it is now becoming a cornerstone of preventive medicine.

The gut microbiota contains over 3 million genes, making it 150 times more genetically varied than the human body. The gut microbiota of each individual is very unique and it has a major contribution to how a person fights disease, digests food, and even his or her mood and psychological processes.

This symbiotic relationship greatly benefits humans. The presence of this normal flora includes microorganisms that are so present in the environment that they can be found in practically all animals from the same habitat.

However, while there are good bacteria found within these native microbes, some of these microbes also include harmful bacteria that can overcome the body’s defences that separate them from vital systems and organs. There are beneficial bacteria in the gut, and there are harmful bacteria that can cross into wider systems and can cause local infections of the GI tract. These infections can then cause infection and inflammation and can also worsen disease states in the body.

What is dybiosis?

The microbiome plays an important role in resisting intestinal overgrowth of externally introduced populations that would otherwise cause disease. In our microbiome, the “good” bacteria compete with the “bad,” with some even releasing anti-inflammatory compounds.

Bacterial dysbiosis produces an endotoxin called lipopolysaccharide (LPS). It is one of the most inflammatory substances known. LPS is also major contributor to the inflammation, which then drives many chronic health conditions and disease states.

These bad bacteria are called dysbiotic bacteria and cause a process called ‘dysbiosis’.

Broadly speaking, dysbiosis indicates the existence of either the wrong microbiota (e.g. overgrowth of bacteria, fungi and/or parasites) and/or the wrong numbers of the right microbiota (imbalances in composition), or either, in the wrong place.

Dysbiosis causes increased gut and intestinal permeability, which can lead to what we call leaky gut, or leaky gut syndrome. Dysbiosis can also consequent lead to up-regulation of inflammatory pathways and lead to increased inflammation in the body.

Dybiosis is implicated in many chronic diseases

Dysbiosis is very common it the western culture and bacterial dysbiosis is now being linked to causing, or exacerbating many health conditions and disease states. Research has found links between bacterial populations, whether normal or disturbed, and the following diseases:

  • Endometriosis
  • Adenomyosis
  • PCOS
  • Asthma
  • Autism
  • Auto-immune conditions
  • Cancer
  • Celiac disease
  • Colitis
  • Inflammatory Bowel Disease
  • IBS
  • Crohn’s Disease
  • Diabetes
  • Eczema
  • Heart disease
  • Malnutrition
  • Multiple sclerosis
  • Arthritis
  • Obesity
  • Metabolic Syndrome

What Causes Dysbiosis?

There are many things that lead to bacterial overgrowth, which then leads to dysbiosis. This is why many people suffer bloating, reflux, nausea, constipation, inflammatory bowel symptoms, and many other gastrointestinal symptoms daily.

Day-to-day risk factors include a western-based diet, overly hygienic living (being too sterile), alcohol, certain medications, hormones and the use of antibiotics.

Mood disorders, stress and being overly busy are also a big factors with creating dysbiosis and something that many overlook, or do not even realise. Yes, stress is a big factor in many gastrointestinal symptoms people experience daily.

With all these factors it means that almost everyone will have some degree of dysbiosis at some point in their life.

Many constantly have dysbiosis and why they often have long-standing digestive symptoms such persistent pain and bloating, constipation, alternating diarrhoea or other digestive imbalances. We also commonly see this with endometriosis and the dreaded “endo belly”

Medications Cause Dysbiosis and Significantly Affect The Microbiome

As mention already, many medications and hormones actually have a toxic affect on the microbiome and can cause dysbiosis. It is crucial to for all of us to understand the consequences of medication use in the gut microbiome. I’ll talk about this in my next post.

The good news, however, is although medications can cause a dysfunctional microbiome quite rapidly, you can begin to restore a healthy microbiome just as quickly through strategic microbiome restore.

Proper Microbiome Restore Protocols

When it comes to proper microbiome restore,  it isn’t just as easy as taking any old probiotic, or a combination of probiotics. Microbiome restore requires and individualised and strain specific approach and it needs to be done in stages with antimicrobials, gut repair and prebiotics as well. Dysbiotic microbes can be hard to treat effectively because they have evolved and adapted to life inside human beings. Consequently, elimination of these organisms requires a similarly evolved and adapted approach. This is all part of the microbiome restore protocol I use with my patients.

A New Understanding

When it comes to the perfect microbiome, researchers have discovered there is no ‘one size fits all’ across various populations. It is important to recognise that not all strains are created equal when it comes to their ability to rebuild a healthy microbiome.

What is now known is that there are only certain types of good probiotic bacteria that have benefit for our gut and microbiome, and that some strains of probiotic bacteria have no benefit. These new finding mean that we need to adopt a strain specific approach when repairing and restoring the microbiome.

From recent investigations and research, the best results are gained by introducing strain specific influential probiotic that have beneficial functions. These specifically influential strains are able to restore each patient’s unique microbiome by promoting the growth of key commensal (symbiotic) groups, but also by improving overall GIT function.

The Importance of Prebiotics

In addition to prescribing a specific probiotic formulation, prebiotic therapy is needed to help support and encourage the establishment of healthy microbiota by significantly increasing the numbers of beneficial bacteria. Without prebiotics, the probiotic bacteria do not grow and this is why they are essential for microbiome restore. Prebiotics are not talked about enough and many people do not realise their importance and often wonder why their probiotics are not working effectively enough.

Prebiotics are also needed to promote the growth of healthy microbiota, begin refurbishment of gut mucosa and improve gastrointestinal immunity. Prebiotics also help with inflammation and also support the integrity of the intestinal barrier, provide healthy immune responses and promote intestinal microbiome balance.

Microbiome Restore Protocols

With emerging research now highlighting the significance of developing and maintaining a healthy microbiome, it is important that everyone knows the importance of appropriate probiotic and prebiotic combinations. By supporting the restoration and repair of our micriobiome, we can all optimise our health, improve treatment outcomes and also help with reducing the risk of many chronic disease states.

If you would like to find out how to restore your microbiome properly, please give my friendly staff a call and find out how I may be able to assist you. Online and in person consultations are available. Some conditions apply.

Regards

Andrew Orr

-No Stone Left Unturned

-Women’s and Men’s Health Advocate

References
  1. Walker A, et al. Phylogeny, culturing, and metagenomics of the human gut microbiota. Trends Microbiol. 2014;22:267–74.
  2. Collado MC, et al. Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus. Lett Appl Microbiol. 2007;45(4):454-60.
  3. Leahy SC, et al. Getting better with bifidobacteria. J Appl Microbiol. 2005;98(6):1303-15.
  4. McFarland LV. Systematic review and meta-analysis of Saccharomyces boulardii in adult patients. World J Gastroenterol. 2010;16(18):2202-22.
  5. Jahn HU, et al. Immunological and trophical effects of Saccharomyces boulardii on the small intestine in healthy human volunteers. Digestion. 1996;57(2):95-104.
  6. Jahn HU, et al. Immunological and trophical effects of Saccharomyces boulardii on the small intestine in healthy human volunteers. Digestion. 1996;57(2):95-104.
  7. Dahan S, et al. Saccharomyces boulardii interferes with enterohemorrhagic Escherichia coli induced signaling pathways in T84 cells. Infect Immun. 2003;71:766-773.
  8. Hsieh H. Versalovic J. The human microbiome and probiotics: Implications for pediatrics. Curr Probl Pediatr Adolesc Health Care. 2008;38(10):309–327.
  9. Lam EK, et al. Enhancement of gastric mucosal integrity by Lactobacillus rhamnosus GG. Life Sci. 2007;80(23):2128-36.
  10. Seth A, et al. Probiotics ameliorate the hydrogen peroxide-induced epithelial barrier disruption by a PKC- and MAP kinase-dependent mechanism. Am J Physiol Gastrointest Liver Physiol. 2008;294(4):G1060-9.
  11. Gibson GR. Roberford M. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr. 1995;125:1401-1412.
  12. Fastinger ND, et al. A novel resistant maltodextrin alters gastrointestinal tolerance factors, fecal characteristics, and fecal microbiota in healthy adult humans. J Am Coll Nutr. 2008;27(2):356-66.
  13. Raninen K, et al. Dietary fiber type reflects physiological functionality: comparison of grain fiber, inulin, and polydextrose. Nutr Rev. 2011;69(1):9-21.
  14. Robison LE. Reeves S. EpiCor® and its immune effects on gut health. Embria Health Sciences, LLC. [Online]. No date. Available from: http://www.embriahealth.com/upload/pdf/EpiCor%20Science%20%20EpiCor%20and%20its%20Immune%20Effects%20on%20Gut%20Health_FINAL.pdf [Cited 16/02/13].
  15. Jensen GS, et al. Antioxidant bioavailability and rapid immune-modulating effects after consumption of a single acute dose of a high-metabolite yeast immunogen: results of a placebo-controlled double-blinded crossover pilot study. J Med Food. 2011 Sep;14(9):1002-10.
  1. Bartoli, C., Frachon, L., Barret, M., Huard-Chauveau, C., Mayjonade, B., Zanchetta, C., … & Roux, F. (2018, May 30). In situ relationships between microbiota and potential pathobiota in Arabidopsis thaliana. The ISME Journal. Retrieved from https://www.nature.com/articles/s41396-018-0152-7#article-info
  2. Berg, R. D. (1996). The indigenous gastrointestinal microflora. Trends in Microbiology, 4(11), 430-435. Retrieved from https://www.sciencedirect.com/science/article/pii/0966842X96100573
  3. Carpenter, S. (2012, September). That gut feeling. Monitor on Psychology, 43(8), 50. Retrieved from http://www.apa.org/monitor/2012/09/gut-feeling.aspx
  4. Clapp, M., Aurora, N., Herrera, L., Bhatia, M., Wilen, E., & Wakefield, S. (2017, September 15). Gut microbiota’s effect on mental health: The gut-brain axis. Clinics and Practice, 7(4), 987. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641835/
  5. NIH Human Microbiome Project. (n.d.). Retrieved from https://hmpdacc.org/
  6. Shepherd, E. S., DeLoache, W. C., Pruss, K. M., Whitaker, W. R., & Sonnenburg, J. L. (2018, May 9). An exclusive metabolic niche enables strain engraftment in the gut microbiota [abstract]. Nature, 557, 434-438. Retrieved from https://www.nature.com/articles/s41586-018-0092-4
  7. The Human Microbiome Project Consortium. (2012, 14 June). Structure, function and diversity of the healthy human microbiome. Nature, 486, 207-214. Retrieved from https://www.nature.com/articles/nature11234
  8. Ursell, L. K., Metcalf, L., K., Wegener Parfry, L., Knight, R. (2012, August). Defining the human microbiome. Nutrition Reviews, 70(Suppl 1), S38-S44. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426293/
Untitled design 6

Why you cannot manage your disease by yourself!

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In this video post, I am going to talk about why you cannot manage your disease by yourself.

Many of us like to think we can treat ourselves, or manage our own disease, or even control every aspect of our lives, but the reality is.. .we can’t.

All to often I see many people trying to manage their own disease state and some of these people are actually healthcare practitioners themselves. The problem is that nobody can manage their own health issue and it is not safe to do so, because of being too close to it. Then the judgement becomes clouded and then this can lead to a vicious cycle of mismanagement and frustration too.

Have a listen to my latest video blog about this issue. I am also talking about this from personal experience and from someone who knows what many people go through too. Today was one of my bad day, so I have an open and honest talk about why you cannot manage your own disease yourself.

No matter who you are, everyone needs help from someone who specialises in the disease that they have. There is help out there. You just have to find the right people to help you.

If you do need help with managing a chronic disease, you can also give my friendly staff a call and find out how I may be able to assist you.

 

Take care

Regards

Andrew Orr

-No Stone Left Unturned

-Women’s and Men’s Health Advocate

Don’t Wait Too Long To Get Help

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In this post I am trying to highlight the importance of not waiting too long to get help, when it comes to pain, or any health condition.

Many people, myself included, with long term pain, chronic health conditions, often have higher than normal pain tolerance and can often leave things too long before seeking professional help. The problem is that the long a health condition is left, the longer pain is left, the harder it can be to treat, or manage on a clinical level.

I know I have spoken about this previously on many posts and why I am very passionate about early intervention for any health condition, especially pain.

During the last couple of weeks I have heard of people leaving things too long and actually ending up dead because of it. Just today, I have had two patients diagnosed with cancer, after leaving symptoms too long before seeking help. It just hits home the importance of seeking help early for any health issue we all face.

Have a listen to my latest post as to why we should not wait too long to get help.

Stress, Distress and De-Stress

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Knowing the difference between stress, distress and de-stress.
Many people do not realise that being constantly busy and being stressed slowly creeps up on them and can one day cause major health issues for them. Being busy for for the sake of being busy is a very common issue these days. We actually refer to it as “The Disease of Being Busy”.

Too many people run their lives and their social status around this term. It is not a badge to be worn with pride at all. When people say that they don’t know how to slow down and relax, this isn’t good. They actually need to learn and retrain the body how to relax and what it feels like to relax.

Being too “Busy” causes stress on the body and can lead to disease, or exacerbate diseases that are already there. It also makes pain worse too.

Life is too short to be busy all the time and just being busy being busy. There is always time in a 24 hour day to take at least 1 hour for self. It is OK to leave emails, leave the washing etc and just be.

At my clinic I help people with learning how to relax and also giving ones body time out with many different forms of treatments. I also work in with counsellors, psychologists, and mindfulness practitioners,  who can teach people coping skills of how to slow down and enjoy life more.

Life is not a race and it is important that we teach children that being too busy is not OK either. It is OK to say “No” to everyone and just take time for self.

Stress and distress can not only cause physical symptoms, such as pain, but it can also cause emotional and psychological issues too. Stress can also kill you.

Symptoms of stress can accumulate over a long period of time and then present with acute symptoms, which can then become chronic. This is why I talk about learning to put yourself first and put your oxygen mask on before attending to others.

It is important to be aware of stress levels and also learning coping strategies and learning that being busy for the sake of being busy, may one day catch up with you and slow you down for good.

Have a listen to my latest video post about stress, distress and de-stress.

Regards

Dr Andrew Orr

-No Stone Left Unturned

-Women’s and Men’s Health Advocate.

doctor and patient

Finding Common Ground To Work With a Good Healthcare Practitioner

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Finding a good healthcare practitioner can be hard. Many have already been jaded and been missed and dismissed by many. This then sets up the expectation that everyone you see, is going to be the same as the last.

The reality is that there are good practitioners out there and it is about finding some common ground, letting go of the past and moving forward with someone who really does want to help you.

Just be careful not to let the past experience with not so good healthcare practitioners be bought in with you when seeing a new healthcare practitioner. It can often then lead to more angst and boundaries and then leading to a good practitioner not being able to really help you.

I hope people can see the point I am trying to get at here. Not all healthcare practitioners are bad. Some are actually amazing and could really help you get your life back to normal again.

It is about working together for your greater health and to do that, there must be understanding on both parts. It is an individualised team approach.

Have a look at my video (below) on this issue.

Take care

Regards

Dr Andrew Orr

-No Stone Left Unturned

-Women’s and Men’s Health Advocate

-The Women’s Health Experts

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Anxiety and Chronic Pain and Chronic Conditions

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Chronic pain and chronic illness can be debilitating. Both pain and chronic conditions can go hand in hand and both can interfere in the daily function in life.

While chronic disease state can cause pain, many do not realise that there are also other factors that exacerbate chronic disease and chronic pain.

Diet, alcohol, drugs, cigarettes, additives in food, chemicals, environment, and emotions can all exacerbate and flare chronic disease state and pain. But some of these things people do not correlate to being part of their daily struggles and increased levels of pain.

Anxiety and depression are two of the things that can exacerbate pain and also lead to chronic pain pathologies. For this post I am going to focus of anxiety because I see so many people who have it. Many people do not realise that they actually have anxiety.

Many people also ignore the signs of anxiety and fob it off as not being able to switch off, or they think too much, or they just do not know how to slow down and relax. Many just fob it off saying that they are busy and don’t have time to stop. They are basically busy being busy. But is it really all those things they think they are?

What is anxiety?

Anxiety is a normal emotion and almost everyone has experienced anxiety at some point.  It is the emotion that people have when something dangerous might happen. Anxiety is closely related to fear. Fear occurs when something dangerous is happening. Anxiety can also activate that fight or flight response and get one adrenalin activated and running through ones veins. Adrenalin is activated to help us get away from danger. The problem with anxiety, danger isn’t really happening. It is the perception of something that may happen. None the less, the body prepares for danger and the nervous system goes into hyperdrive and the fight or flight response is activated.

As mentioned before, anxiety can also be when something dangerous is seemed to be pending, or hasn’t happened yet, though we perceive it could.  This is why people with anxiety always tend to be nervous. They are nervous in their feelings, their body and their behaviours as well. These people are quite literally waiting for the possibility of something dangerous to happen, or needing to get up and get moving. They literally cannot sit still.

Anxiety can also be divided into different aspects: feelings, physical manifestations, thinking, and behaviours.

Feelings

A number of feelings are associated with anxiety. It can cause one to feel apprehensive, feel alarmed, feel tension, feel nervousness, feel doubtful and also make one feel out of control.

Physical manifestations

Anxiety can also lead to physical manifestation in the body as well. It can cause muscle tension, increased hear rate, palpitations, increased blood pressure, heaviness in the chest, gastrointestinal upset and urgency, cold hands and feet, increased sweating, dizziness and increased energy and even cause the body to shake.

Thinking

Anxiety can also influence the way we think. It can cause increased worry, increase focus on things that have not occurred, increased focus on possible danger and all of the consequences that could occur, increased thinking of the worst case scenarios of what could happen to one self and anxiety can also cause increased thinking and overthinking in general.

Behaviours

Anxiety can also influence the way be behave.  It can cause restlessness, avoidance of activities ( for fear of perceived danger), cause nervousness, inability to sit still, need to get up and move all the time, and cause difficulty in completing things.

Sometimes, anxiety becomes persistent and then can get in the way of day-to-day life. When anxiety is persistent and interfering in day-to-day life, it’s considered no longer normal. It is then considered a disorder.

Anxiety and pain

Everyone experiences pain at some point in their life, but for those with anxiety and depression, pain can become intense and very hard to treat.

Anxiety is now known to be one the most common conditions that accompanies chronic pain. Anxiety tends to go hand in hand with chronic pain, because pain is a danger signal.  When we get pain it is to signal danger that something is wrong in the body and requires attention.  Pain then sets of the warning system that then leads the nervous system to respond. This then often leads to that fight or flight response talked about previously.

The nervous system’s response to pain just in the same way it responds to danger. This can be in the following ways:

  • Feelings of alarm, apprehension and distress
  • Increased reactivity of the body, such as
  • Increased muscle tension,
  • Increased heart rate ad blood pressure,
  • Gastrointestinal reactivity and digestive pain and upset
  • Increased cognitive focus on the pain, and then a tendency to worry and catastrophize about it
  • Avoidance behaviours, such as guarding, resting, staying home and not engaging in activities that might bring about or increase pain

In acute pain, these responses might be quite helpful. These feelings of pain and fear allow someone to seek help in order to prevent further injury.

In chronic pain, these feelings become anxiety and avoidance behaviours. When someone has chronic pain for a long time, the anxiety and avoidance behaviours can become chronic. The chronic anxiety leads to a chronic sense of alarm or distress, which makes patients nervous and can’t sit still and finds it very hard to relax and recover.

Anxiety and chronic pain

Chronic pain also affects the brain and thought patterns and it can lead to a chronic focus on pain, which pre-occupies the attention of the pain sufferer. Everyday decisions seem to turn on how much pain the patient has at any given time. It also leads to then nervous system to become over reactive. This can then lead to chronic muscle tension, which can switch pain pathways on more and this then leads to more pain. Chronic avoidance behaviours can then lead to an increasing sense of social isolation, inactivity, muscles loss and then not being able to cope or function physically and mentally. Daily life literally can become an effort and the person actually become disabled.

When the body reaches this state the nervous system has become stuck in the vicious cycle of constant reactivity. Pain pathways become more reactive and harder to switch off and pain levels can become very hard to manage. This state of reactivity is associated with a condition called central sensitization. This is where acute pain has becomes chronic and then this goes hand in hand with anxiety and other mood disorders.

Anxiety can present differently in each person

Anxiety can present very differently in each person and chronic disease states can also trigger anxiety. Anxiety can also exacerbate a chronic health condition too. It can be a vicious cycle that keeps going around and around.

Everyone’s cause of anxiety is different and it’s often a combination of factors that leads someone to feel the way they do. Many do not even realise they are suffering anxiety as mentioned before.

It’s important to remember that you can’t always identify the cause of anxiety, or change difficult circumstances. You cannot always be in control of every situation either.

Recognise the signs and seek professional help

The most important thing is to recognise the signs and symptoms and seek advice and support.

There are people that specialise in managing chronic pain. Good pain management programs should use a multi-modality treatment and management approach consisting of the most effective treatments for anxiety, such as counselling and psychology, medications, diet and lifestyle changes, exercise and other therapies that can assist with pain and anxiety.

With the right help and seeing the right people, it is possible to get ones life back despite having chronic pain, and in the process overcome anxiety. The one thing I always explain to people it that you will not be able to do this on your own. You will need help from qualified professionals. No amount of Dr Google, or advice from friends and family is going to be able to help you get through this without the help of qualified professionals trained to help in this area of healthcare.

If you are experiencing long term pain and could also be suffering from chronic anxiety, please go and talk to your healthcare provider. Many people are unaware that they have anxiety and this is actually exacerbating their current pain. Your healthcare practitioner can also talk to you about effective pain management and also help you seeking help and getting coping skills for your anxiety as well.

Beyond Blue has a very simple Anxiety checker (click here) and I urge everyone to take the test, especially those with chronic long-term pain and health issues.

Please remember that there is help out there. Please do not suffer in silence thinking that there is no help, or no end in sight for your pain and your anxiety as well.

Take care

Regards

Dr Andrew Orr

-No Stone Left Unturned

-Women’s and Men’s Health Advocate

01 Dr Andrew Orr

 

 

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Foods That Can, and Do, Cause Constipation

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Many people have trouble moving their bowels on a daily basis and are none the wiser as to why this happens to them. Many do not realise how bad for their health it is not to move your bowels daily and many people just think it is normal for them to not need to get things moving each morning.

Of course some people have conditions, that cause constipation, and these need to be ruled out too.

Conditions such as Endometriosis, Pelvic Inflammatory disease, IBS and other bowel disorders can all cause chronic constipation and inflammation in the bowel

But for most people the clogging of the back passage is caused by what they are eating and lack of foods that contain real fibre and water to keep the bowels moving.

Lack of proper hydration and stress is also a factor too. But when it comes to proper fibre, many people are just eating the wrong foods. Many of the foods people are having on a daily basis, thinking it is fibre, are actually closer to being cardboard and the effects on the bowel are just as bad.

So what are the foods that are causing a blockage in peoples elimination pipes.

1.Fast Or Prepared Foods

Those ready made meals and takeaway meals may be convenient, but they could cause a backup. Most are low in fiber, which you need to help food move through your system.

2.Fried Food

Fried foods are full of fat, lack fiber and are hard to digest. When food moves through your colon slowly, too much water can be taken out of it. That makes for a hard, dry stool.

3.Cakes, Sweets and Pastries

Pastries, cookies, and other treats with refined sugar are low in fiber and fluids, and high in fat. Many people think that because they contain grains, that they are good for you. But nothing could be further from the truth. Wheat grains are actually inflammatory and cause disruption to the digestive system. There is actually more fiber in whole foods such as fruit and vegetable. Grains are refined grains are not good if you’re having trouble keeping things moving. Satisfy your sweet tooth with some fresh fruits and yogurt. Your tummy will thank you for it.

4.Breads

Bread is basically made from flour and water and what does flour and water make? Glue that’s what it makes! That is what it turns to in your stomach and bowel too. Plus refined flours are made from inflammatory grains and these cause disruption to your digestion and bowel too. Too much bread will give you hard, dry stools and also mess with your digestion. It’s also made with low-fiber flour. The whole grain variety may be a little bit better, but not much. If your digestive system is shot and you are having trouble getting things to move, time to ditch the bread. We don’t need to eat it anyway.

5.Caffeine

A couple cups of teas coffee makes some people race to the bathroom, but it can have the opposite effect, too. The caffeine in coffee and tea are diuretics and soft drinks can keep your body from holding onto water, and you need water to stay regular. If you’re constipated, check how much tea and coffee you might be drinking and make sure you drink plenty of water after each cup of caffeine.

6.Alcohol

Alcohol can definitely dehydrate the body make it hard for your body to hang onto water. This can then cause gastrointestinal inflammation, upset the liver function and then cause constipation.

7.Eggs

Eggs are really good for us and they are high in protein but low in fiber. But, you don’t have to stop eating them though. Just add some high-fiber foods into the mix. Add some greens with them when you eat them. Try an omelet with fresh spinach and tomatoes.

8.Well Done Meat

Meat is a great source of protein but when its well-done and over cooked, it is lacking in fiber, that juicy steak needs to be a little less cooked (medium rare) and balanced with a side of nice green veggies, or salad. This will help get it comfortably through your digestive system.

 

Some Fiber Facts.

Veggie and whole Fruits (not dried fruits) have more fiber than cereals and grains and as they contain water and other nutrients needed to keep the bowel hydrated and moving properly. Time to ditch the cereals and start eating some more whole foods instead.

Oh… and don’t forget the prebiotics and probiotics to keep healthy gut flora/microbiome and keep the digestive system functioning properly.

Of course we should drink plenty of water and also make sure you get some electrolytes into your diet daily too. This will help keep your bowels working the way they should work, rather than the way they have been.

If you are having trouble with chronic constipation and getting your bowels to move daily, then give my clinic a call and book in a consultation where we can help you get your digestion back on track again.

Take care

Regards

Dr Andrew Orr

-No Stone Left Unturned

-Women’s and Men’s Health Expert

01 Dr Andrew Orr 1

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Western Diet Permanently Alters the Immune System & Alters Gene Expression

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For many years we have been trying to explain to people how their diet is a major factor in their current health and how a poor diet can actually cause expression of many inflammatory disease states within the body. There is now research which shows how the western diet permanently alters the immune system and alters gene expression.

New research has shown that our immune system responses to the Western diet very similar to how it reacts to infection by dangerous bacteria. The research was led by the University of Bonn in Germany and published in the journal Cell.

One of the disturbing results of the study is that the longer we consume a high GI, highly refined foods, and Western diet, that it can make the immune system become hyper-responsive to inflammation triggers. We know that a diet in highly processed foods and refined carbohydrates actually causes high inflammation in the body.

The longer we eat this way, these long-term changes may contribute to type 2 diabetes, arteriosclerosis, inflammatory bowel conditions, cancers,  gynaecological conditions,  and several other conditions wherein inflammation is thought to play a part, and which have been linked to consumption of a highly refined Western based diet.

The Western diet altered gene expression

The new research showed that just after just 1 month, there were changes throughout the bodies that are similar to the strong inflammation reactions that occur in bacterial infections. The researchers showed that an unhealthy high GI/highly refined diet led to increases in certain immune cells, which were a sign of inflammation and an infection like process. They also found that the Western diet had switched on many genes in the body that would also express many disease states and inflammatory processes in the body.

The researchers concluded that  findings highlight the dramatic impact that the wrong kind of food can have, and that they have important implications for society, especially for children who grow up with this highly inflammatory based diets and consume them longer.

The researchers concluded that adults and children have a choice of what they eat every day. We should enable everyone, especially children,  to make conscious decisions regarding their dietary habits. The new research also highlighted that dietary habits and the foundations of what a healthy diet is, need to become more prominent in our education system and it needs to start at a younger age. We also need to re-educate adults on what a healthy diet is as well

At my clinic, we can help people to know what a healthy diet is and this education is also passed onto people we help with inflammatory disease states.

We always promote a Primal/Low GI/grain free diet to all our patients so that they can be healthier, have less inflammation in their bodies and live longer and happier lives.

Regards

Dr Andrew Orr

-No Stone Left Unturned

-Women’s and Men’s Health Expert

01 Dr Andrew Orr 1