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Microbiome

The Importance Of Properly Restoring The Microbiome For Optimum Health

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One of the things I teach my patients is the importance of properly restoring the microbiome for optimum health and also reducing inflammation in the body.

Many people’s daily bloating, fluid retention, gastrointestinal symptoms, health issues, chronic disease states are being exacerbated by an unhealthy balance in this unique ecosystem we call the microbiome.

The problem is that many people do not really understand the importance of the microbiome, and even many healthcare professionals do not fully understand how to help with proper microbiome repair and restore.

Many people are also led to believe that by just taking probiotics, that this is enough to restore the healthy bacteria in the gut/microbiome.

I wish it was that easy, but it isn’t and this is why many people continue to have gastrointestinal issues, inflammation and chronic health issues, despite thinking that are doing the right thing for their gut health.

What is the Microbiome?

The human gastrointestinal tract (GIT) is host to an extraordinary amount of microorganisms composed of bacteria, viruses and microbes, collectively known as the microbiome. The microbiome is the name given to all of the genes inside these microbial cells.

Every human being has anywhere between 10 trillion and 100 trillion microbial cells all working together in a symbiotic relationship. This benefits both the microbes and their hosts, as long as the body is in a healthy state.

Recent scientific advances in genetics mean that humans know a lot more about the microbes in the body. There has been lot of time and money put into researching the interactions within the human body’s ecosystem and their relevance to health and disease.

The two terms ‘microbiota’ and ‘microbiome’ are often used to mean the same thing and are used interchangeably. I will explain the differences between them and how both are being used and researched in modern medicine.

You exist in a symbiotic relationship with your bacterial ecosystem, and there is a two-way relationship that makes your health inseparable from that of your microbiome and vice versa.

The benefits of a healthy microbiome/microbiota

The benefits of a healthy microbiome/microbiota, extend beyond the gut and digestive system and has a significant systemic impact on some the following:

  • Nutrient metabolism
  • Body composition (weight)
  • Cardiovascular health,
  • Chronic disease states
  • Inflammation in the body
  • Pain pathways
  • Immunity
  • Mental Health
  • Neuroendocrine function
  • Gene Expression

What is the Microbiota

The gut microbiota used to be called the microflora of the gut. The importance of the microbiota has been known for a long time, but now medical science is discovering just how important it is, and it is now becoming a cornerstone of preventive medicine.

The gut microbiota contains over 3 million genes, making it 150 times more genetically varied than the human body. The gut microbiota of each individual is very unique and it has a major contribution to how a person fights disease, digests food, and even his or her mood and psychological processes.

This symbiotic relationship greatly benefits humans. The presence of this normal flora includes microorganisms that are so present in the environment that they can be found in practically all animals from the same habitat.

However, while there are good bacteria found within these native microbes, some of these microbes also include harmful bacteria that can overcome the body’s defences that separate them from vital systems and organs. There are beneficial bacteria in the gut, and there are harmful bacteria that can cross into wider systems and can cause local infections of the GI tract. These infections can then cause infection and inflammation and can also worsen disease states in the body.

What is dybiosis?

The microbiome plays an important role in resisting intestinal overgrowth of externally introduced populations that would otherwise cause disease. In our microbiome, the “good” bacteria compete with the “bad,” with some even releasing anti-inflammatory compounds.

Bacterial dysbiosis produces an endotoxin called lipopolysaccharide (LPS). It is one of the most inflammatory substances known. LPS is also major contributor to the inflammation, which then drives many chronic health conditions and disease states.

These bad bacteria are called dysbiotic bacteria and cause a process called ‘dysbiosis’.

Broadly speaking, dysbiosis indicates the existence of either the wrong microbiota (e.g. overgrowth of bacteria, fungi and/or parasites) and/or the wrong numbers of the right microbiota (imbalances in composition), or either, in the wrong place.

Dysbiosis causes increased gut and intestinal permeability, which can lead to what we call leaky gut, or leaky gut syndrome. Dysbiosis can also consequent lead to up-regulation of inflammatory pathways and lead to increased inflammation in the body.

Dybiosis is implicated in many chronic diseases

Dysbiosis is very common it the western culture and bacterial dysbiosis is now being linked to causing, or exacerbating many health conditions and disease states. Research has found links between bacterial populations, whether normal or disturbed, and the following diseases:

  • Endometriosis
  • Adenomyosis
  • PCOS
  • Asthma
  • Autism
  • Auto-immune conditions
  • Cancer
  • Celiac disease
  • Colitis
  • Inflammatory Bowel Disease
  • IBS
  • Crohn’s Disease
  • Diabetes
  • Eczema
  • Heart disease
  • Malnutrition
  • Multiple sclerosis
  • Arthritis
  • Obesity
  • Metabolic Syndrome

What Causes Dysbiosis?

There are many things that lead to bacterial overgrowth, which then leads to dysbiosis. This is why many people suffer bloating, reflux, nausea, constipation, inflammatory bowel symptoms, and many other gastrointestinal symptoms daily.

Day-to-day risk factors include a western-based diet, overly hygienic living (being too sterile), alcohol, certain medications, hormones and the use of antibiotics.

Mood disorders, stress and being overly busy are also a big factors with creating dysbiosis and something that many overlook, or do not even realise. Yes, stress is a big factor in many gastrointestinal symptoms people experience daily.

With all these factors it means that almost everyone will have some degree of dysbiosis at some point in their life.

Many constantly have dysbiosis and why they often have long-standing digestive symptoms such persistent pain and bloating, constipation, alternating diarrhoea or other digestive imbalances. We also commonly see this with endometriosis and the dreaded “endo belly”

Medications Cause Dysbiosis and Significantly Affect The Microbiome

As mention already, many medications and hormones actually have a toxic affect on the microbiome and can cause dysbiosis. It is crucial to for all of us to understand the consequences of medication use in the gut microbiome. I’ll talk about this in my next post.

The good news, however, is although medications can cause a dysfunctional microbiome quite rapidly, you can begin to restore a healthy microbiome just as quickly through strategic microbiome restore.

Proper Microbiome Restore Protocols

When it comes to proper microbiome restore,  it isn’t just as easy as taking any old probiotic, or a combination of probiotics. Microbiome restore requires and individualised and strain specific approach and it needs to be done in stages with antimicrobials, gut repair and prebiotics as well. Dysbiotic microbes can be hard to treat effectively because they have evolved and adapted to life inside human beings. Consequently, elimination of these organisms requires a similarly evolved and adapted approach. This is all part of the microbiome restore protocol I use with my patients.

A New Understanding

When it comes to the perfect microbiome, researchers have discovered there is no ‘one size fits all’ across various populations. It is important to recognise that not all strains are created equal when it comes to their ability to rebuild a healthy microbiome.

What is now known is that there are only certain types of good probiotic bacteria that have benefit for our gut and microbiome, and that some strains of probiotic bacteria have no benefit. These new finding mean that we need to adopt a strain specific approach when repairing and restoring the microbiome.

From recent investigations and research, the best results are gained by introducing strain specific influential probiotic that have beneficial functions. These specifically influential strains are able to restore each patient’s unique microbiome by promoting the growth of key commensal (symbiotic) groups, but also by improving overall GIT function.

The Importance of Prebiotics

In addition to prescribing a specific probiotic formulation, prebiotic therapy is needed to help support and encourage the establishment of healthy microbiota by significantly increasing the numbers of beneficial bacteria. Without prebiotics, the probiotic bacteria do not grow and this is why they are essential for microbiome restore. Prebiotics are not talked about enough and many people do not realise their importance and often wonder why their probiotics are not working effectively enough.

Prebiotics are also needed to promote the growth of healthy microbiota, begin refurbishment of gut mucosa and improve gastrointestinal immunity. Prebiotics also help with inflammation and also support the integrity of the intestinal barrier, provide healthy immune responses and promote intestinal microbiome balance.

Microbiome Restore Protocols

With emerging research now highlighting the significance of developing and maintaining a healthy microbiome, it is important that everyone knows the importance of appropriate probiotic and prebiotic combinations. By supporting the restoration and repair of our micriobiome, we can all optimise our health, improve treatment outcomes and also help with reducing the risk of many chronic disease states.

If you would like to find out how to restore your microbiome properly, please give my friendly staff a call and find out how I may be able to assist you. Online and in person consultations are available. Some conditions apply.

Regards

Andrew Orr

-No Stone Left Unturned

-Women’s and Men’s Health Advocate

References
  1. Walker A, et al. Phylogeny, culturing, and metagenomics of the human gut microbiota. Trends Microbiol. 2014;22:267–74.
  2. Collado MC, et al. Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus. Lett Appl Microbiol. 2007;45(4):454-60.
  3. Leahy SC, et al. Getting better with bifidobacteria. J Appl Microbiol. 2005;98(6):1303-15.
  4. McFarland LV. Systematic review and meta-analysis of Saccharomyces boulardii in adult patients. World J Gastroenterol. 2010;16(18):2202-22.
  5. Jahn HU, et al. Immunological and trophical effects of Saccharomyces boulardii on the small intestine in healthy human volunteers. Digestion. 1996;57(2):95-104.
  6. Jahn HU, et al. Immunological and trophical effects of Saccharomyces boulardii on the small intestine in healthy human volunteers. Digestion. 1996;57(2):95-104.
  7. Dahan S, et al. Saccharomyces boulardii interferes with enterohemorrhagic Escherichia coli induced signaling pathways in T84 cells. Infect Immun. 2003;71:766-773.
  8. Hsieh H. Versalovic J. The human microbiome and probiotics: Implications for pediatrics. Curr Probl Pediatr Adolesc Health Care. 2008;38(10):309–327.
  9. Lam EK, et al. Enhancement of gastric mucosal integrity by Lactobacillus rhamnosus GG. Life Sci. 2007;80(23):2128-36.
  10. Seth A, et al. Probiotics ameliorate the hydrogen peroxide-induced epithelial barrier disruption by a PKC- and MAP kinase-dependent mechanism. Am J Physiol Gastrointest Liver Physiol. 2008;294(4):G1060-9.
  11. Gibson GR. Roberford M. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr. 1995;125:1401-1412.
  12. Fastinger ND, et al. A novel resistant maltodextrin alters gastrointestinal tolerance factors, fecal characteristics, and fecal microbiota in healthy adult humans. J Am Coll Nutr. 2008;27(2):356-66.
  13. Raninen K, et al. Dietary fiber type reflects physiological functionality: comparison of grain fiber, inulin, and polydextrose. Nutr Rev. 2011;69(1):9-21.
  14. Robison LE. Reeves S. EpiCor® and its immune effects on gut health. Embria Health Sciences, LLC. [Online]. No date. Available from: http://www.embriahealth.com/upload/pdf/EpiCor%20Science%20%20EpiCor%20and%20its%20Immune%20Effects%20on%20Gut%20Health_FINAL.pdf [Cited 16/02/13].
  15. Jensen GS, et al. Antioxidant bioavailability and rapid immune-modulating effects after consumption of a single acute dose of a high-metabolite yeast immunogen: results of a placebo-controlled double-blinded crossover pilot study. J Med Food. 2011 Sep;14(9):1002-10.
  1. Bartoli, C., Frachon, L., Barret, M., Huard-Chauveau, C., Mayjonade, B., Zanchetta, C., … & Roux, F. (2018, May 30). In situ relationships between microbiota and potential pathobiota in Arabidopsis thaliana. The ISME Journal. Retrieved from https://www.nature.com/articles/s41396-018-0152-7#article-info
  2. Berg, R. D. (1996). The indigenous gastrointestinal microflora. Trends in Microbiology, 4(11), 430-435. Retrieved from https://www.sciencedirect.com/science/article/pii/0966842X96100573
  3. Carpenter, S. (2012, September). That gut feeling. Monitor on Psychology, 43(8), 50. Retrieved from http://www.apa.org/monitor/2012/09/gut-feeling.aspx
  4. Clapp, M., Aurora, N., Herrera, L., Bhatia, M., Wilen, E., & Wakefield, S. (2017, September 15). Gut microbiota’s effect on mental health: The gut-brain axis. Clinics and Practice, 7(4), 987. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641835/
  5. NIH Human Microbiome Project. (n.d.). Retrieved from https://hmpdacc.org/
  6. Shepherd, E. S., DeLoache, W. C., Pruss, K. M., Whitaker, W. R., & Sonnenburg, J. L. (2018, May 9). An exclusive metabolic niche enables strain engraftment in the gut microbiota [abstract]. Nature, 557, 434-438. Retrieved from https://www.nature.com/articles/s41586-018-0092-4
  7. The Human Microbiome Project Consortium. (2012, 14 June). Structure, function and diversity of the healthy human microbiome. Nature, 486, 207-214. Retrieved from https://www.nature.com/articles/nature11234
  8. Ursell, L. K., Metcalf, L., K., Wegener Parfry, L., Knight, R. (2012, August). Defining the human microbiome. Nutrition Reviews, 70(Suppl 1), S38-S44. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426293/
IBS

Managing Irritable Bowel Syndrome & Inflammatory Bowel Disease

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Irritable Bowel Syndrome, or IBS, is a problem that affects a staggering 3million people, or more, in Australia and about 20% of people world-wide. It is a condition that has baffled doctors for years. There is no single cause, no specific treatment and, as yet, no cure.

But first let’s look at some general information on IBS.

IBS is more common in women than in men and occurs more often in younger people. IBS is usually ongoing, and there are some times when symptoms are worse than other times. Having IBS does not mean you are more likely to develop colon cancer later in life.

Symptoms of IBS

Some people with IBS mainly have constipation, others have diarrhoea. Many people with IBS alternate between periods of constipation and diarrhoea.

Symptoms include:

  • Cramps and bloating in your lower abdomen, which usually get better after having a bowel motion or passing wind
  • Pain that can be a sharp or dull feeling
  • Constipation: feeling that you have not managed to empty your bowels completely, having bowel motions less often, straining to pass a motion or passing small, hard stools
  • Diarrhoea: having bowel motions too often and passing loose stools
  • Flatulence, or wind, and/or rumbling noises from your abdomen
  • Needing to rush to the toilet
  • Headaches
  • Mucus in your stools

Some of these symptoms can also be from other inflammatory bowel diseases such as Crohns disease and Ulcerative Colitis, which sometimes get categories as IBS.

But some of the symptoms above can also be part of having endometriosis and many women who are diagnosis with IBS, in fact have endometriosis. They then have all the testing for IBS, Crohn’s, ulcerative colitis etc (colonoscopy etc) as these don’t find anything and then these women are often told by doctors they are at a loss to what is happening. This is why endometriosis often takes up to 12 years for definitive diagnosis, which is terrible.

IBS triggers

The cause of IBS is not known, but certain things can trigger its symptoms, including:

  • Stress
  • Depressed mood
  • Food poisoning
  • Tummy bug
  • Virus
  • Certain foods and drinks
  • Some medication
  • Some people find avoiding alcohol, caffeine and nicotine can reduce their IBS symptoms

As said before some women suffer more acutely from symptoms of IBS just before, or during, their menstrual cycle. IBS symptoms can also mean that they have a condition called Endometriosis. Many times these conditions can be overlooked and they can be present at the same time, along with bladder issues as well.

Lactose and wheat intolerance and wheat may be a cause and needs to be assessed before permanent changes to diet are made. Wheat grains are inflammatory to the bowel anyway and they should be removed if anyone does have inflammatory bowel issues.

Treatments

There are a few medical treatments available but results can be varying. Many people with severe IBS end up on steroids to settle inflammation in the bowel. There are also other medications to slow bowel motility and reduce inflammation as well.

Dietary and lifestyle changes may assist with the management of endometriosis.

There are also other complementary therapies and treatments that may be assistance and combined with medical interventions, or other interventions..

Studies have shown that strain specific probiotic bacteria may assist with inflammatory bowel conditions such as ulcerative colitis and IBS. But, this needs consultation with a qualified healthcare professional to treat disease properly. Self-prescribing is not an option for this disease that affects over 3 million people here in Australia alone.

With any disease state such as IBS, there needs to be an individualised approach, not a one treatment fix all approach, because everyone is uniquely difference in their symptoms they experience and what their triggers are. There also needs to be a multimodality approach because many times IBS overlaps with conditions such as endometriosis for women, and other inflammatory conditions in men.

If you have IBS or inflammatory bowel disease and need help and assistance in managing your symptoms better, please give my friendly staff a call and they will explain how I may be able to assist you.

Regards

Andrew Orr

-No Stone Left Unturned

-Women’s and Men’s Health Advocate

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Reasons You May Be Gaining Weight

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Weight loss is something that I get asked about often and not many people understand that it is more about fat loss, rather than weight loss, when it comes to being healthy. There are many reasons that people may be gaining weight and most of the common cause are lack of exercise and what people put in their mouths.

There are health issues that may affect your weight also, but at the end of the day, dietary and lifestyle changes are still needed to remain in the healthy weight range for your health. In this article I will look at the many factors that could be causing someone to gain fat and not be able to lose it.

It May Not Just Be Your Food Intake

If you started taking in more calories than usual, or increase your high GI foods, or cut back on exercise, you wouldn’t be surprised if the numbers on the scale crept higher. Just remember that scales aren’t an accurate assessment of body fat and that muscle does weigh more that fat. It is the waist size that is the true measurement we want people to focus on. We should be more worried about waist gain, rather than weight gain.  But what if you’re doing everything the same as you always do, and your weight still goes up? It’s time to delve a little deeper into what else might be going on.

Lack of Sleep

There are two things that can affect your when you aren’t getting enough sleep and may have an impact on weight gain. First, if you’re up late, the odds are greater that you’re doing some late-night snacking, which means more intake of foods that may not be appropriate. The other reason involves what’s going on in your body when you’re sleep-deprived. This leads to running on adrenalin and increased cortisol levels as well. Changes in hormone levels increase hunger and appetite and also make you feel not as full after eating.

Stress

When life’s demands get too intense, our bodies go into survival mode. That fight or flight response kicks in and adrenalin and Cortisol, the “stress hormone,” is secreted, which causes an increase in appetite. Cortisol also makes you store fat. And of course, we may reach for high-calorie comfort foods in times of stress as well. This combination is a perfect breeding ground for weight gain.

Antidepressants and other Medications

An unfortunate side effect from some antidepressants is weight gain. Most antidepressants will give people a weight gain of around 3kgs per year of taking them. Talk to your healthcare practitioner about making changes to your treatment plan if you think your antidepressant is causing weight gain. There are natural options that can help with depression, without all the side effects. But never stop or change your medication on your own. Realize that some people experience weight gain after beginning drug treatment simply because they’re feeling better, which leads to a better appetite. Also, depression itself can cause changes in weight.

Steroids and Hormones

Anti-inflammatory steroid medications like prednisone are notorious for causing weight gain. All of the fertility hormones and hormone replacement drugs are steroidal based and cause weight gain too. Fluid retention and increased appetite are the main reasons. Some people may also see a temporary change in where their body holds fat while taking steroids.  Places like the face, the belly, or the back of the neck are all areas where you can see increase fluid retention. If you’ve taken steroids for more than a week, don’t stop them abruptly. That can lead to serious problems. They need to be tapered down slowly and weaned off properly. Check with your doctor first. Drugs That May Cause Weight Gain.

Several other prescription drugs are linked to weight gain. The list includes antipsychotic drugs (used to treat disorders like schizophrenia and bipolar disorder), along with medications to treat migraines, seizures, high blood pressure, and diabetes. Work with your doctor to find a medication that treats your symptoms and lessens side effects.

The Contraceptive Pill

Combination birth control pills (estrogen and progestin) do weight gain and fluid retention. There are other contraceptive methods that do not cause weight gain and fluid retention and have lower side effect profiles. If you’re still concerned about possible weight gain, talk to your healthcare practitioner.

Thyroid Issues

Thyroid issues can definitely be a big factor in weight gain. If your thyroid (the butterfly-shaped gland in the front of your neck) is not making enough thyroid hormone, you’re probably feeling tired, weak, and cold, and gaining weight. Without enough thyroid hormone, your metabolism slows, making weight gain more likely. Even a thyroid functioning at the lower end of the normal range might cause weight gain. Treating hypothyroidism with medication may reverse some of the weight gain.

Menopause

Most women do gain some weight around the time of menopause, but hormones probably aren’t the only cause. Aging slows your metabolism, so you burn fewer calories. We need women to realise this reality, which isn’t always easy to accept. Changes in lifestyle (such as exercising less) play a role in weight and waist gain. But where you gain weight may be related to menopause, with fat accumulating around your waist more than your hips and thighs. There are ways to control this in menopause too.

Cushing’s Syndrome

Weight gain is a common symptom of Cushing’s syndrome, a condition in which you are exposed to too much of the stress hormone cortisol, which in turn causes weight gain and other abnormalities. You can get Cushing’s syndrome if you take steroids for asthma, arthritis, or lupus. It can also happen when your adrenal glands make too much cortisol, or it could be related to a tumor. The weight gain may be most prominent around the face, neck, upper back, or waist.

Polycystic Ovary Syndrome (PCOS)

PCOS is a common hormonal problem in all women of childbearing age. It is the most common gynaecological disorder in women and is becoming more prevalent due to our high GI diets and being passed on through genetic and hereditary link. Some women with PCOS grow many small cysts on their ovaries, some do not and only have the syndrome and associated symptoms. The condition leads to hormone imbalances that affect a woman’s menstrual cycle and can lead to extra body hair and acne. Women with this condition are resistant to insulin (the hormone that controls blood sugar), so it may cause weight gain. Many women with PCOS are normal, or underweight too. Women with PCOS are also at higher risk of diabetes. The weight tends to collect around the belly, putting these women at greater risk for heart disease and diabetes.

Quitting Smoking

Quitting smoking is one of the best things you can do for your health. When you quit, you may gain some weight, but perhaps less than you think. On average, people who stop smoking gain less than 10 kilograms. You should stop feeling hungrier after several weeks, which will make it easier to help lose any weight you gained.

Rules If You Do Gain Weight

Rule 1:

Don’t stop taking any medications without first consulting your doctor. Recognize the importance of the drug you’re taking. It may be critical to your health. Also, something else may be causing you to gain weight. Your doctor can help you figure out what’s going on. There are also natural options that you may take also.

Rule 2:

Don’t compare yourself to other people taking the same drug. Not all people experience the same side effects on the same drug. Even if a drug caused someone else to lose weight, the same might not be true for you. Please do not Dr Google, or take advice off anyone other than a qualified healthcare professional.

Rule 3:

Remember that if the weight gain is just from water retention, it’s not permanent weight or fat. Once you’re done taking the drug or your condition is under control, the puffiness from fluid retention may ease. Stick to a lower GI diet in the meantime too. High GI foods such as breads, cereals, cakes, pasta, sugars etc, all make the body store fats and stop the burning of fats and cause inflammation.

Rule 4:

Check with your healthcare practitioner about another medication you can take. In many cases, your healthcare practitioner can switch you to another medication that might not have the same side effects. There are also natural options that you may be able to take without all the nasty side effects of your medication

Rule 5:

Learn if the weight gain is from a decrease in metabolism — from either a medical condition or medication. And if so, take the time to participate in metabolism-raising activities. Get moving!

Also realise that it is waist gain you need to worry about, not weight gain. Many people obsess unnecessarily over weight gain and the scales. When you start to exercise, you may in fact be putting on muscle (which is great) and this will equate to the scales being heavier.

Fat does not weigh as much as muscle per square centimeter , so sometimes you wont realise you have actually lost fat and gained muscle. This is why waist measurement, not weight measurement, is the most accurate way to measure proper fat lose and proper waist and weight management.

A woman’s healthy waist size should be 80cm’s, or below and a man’s healthy waist size should be 94cm’s, or below. Take from the belly button level.

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A kilo of fat, versus a kilo of muscle

At my clinic we can help and assist you with weight management and more importantly waist management. We have specially tailored fat loss and weight loss programs to assist you burn fats, increase muscle and do weight loss the correct way.

If you want to get healthy, feel great and look great for next summer and years to come, please give the clinic a call and book in for a consultation.

Regards

Andrew Orr

-No Stone Left Unturned

-Women’s and Men’s Health advocate

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Food additives and emulsifiers may increase inflammation and anxiety

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A wide range of foods contain ingredients that we call emulsifiers. A new study has shown that these compounds can produce both physiological and behavioural changes.

Bread and many other common foods we eat daily contain emulsifiers and other additives.

Food additives have always generated a great deal of attention as they can lead to exacerbating many health conditions, or even be the cause of some health issues as well. Recently, emulsifiers have been drawing fire and rightfully so.

Manufacturers have been using these chemicals to alter food’s texture and extend its shelf life for years and they are not good for our health. These emulsifiers are found in many foods such as bread, chocolate, margarine, processed meats, and more.

Earlier studies have shown that emulsifiers can alter the microbiome of mice, causing low-grade inflammation and increasing the risk of obesity and metabolic disorders. But now a study in humans concluded that gut bacteria “can be directly impacted by these commonly used food additives, and these additives also subsequently drives intestinal inflammation.”

Recently, researchers from Georgia State University in Atlanta set out to see if these emulsifiers also influenced mental wellbeing. The focussed on two commonly used emulsifiers — carboxymethylcellulose (CMC) and polysorbate-80 (P80).

The Microbiome and Psychological health

In many recent studies scientists have already described a clear pathway between the gut and the brain. These studies have shown that our gut health and the health of our gut bacteria can have a substantial influence on our mental well-being. Most of the studies concluded that lack of good bacteria in the gut and overuse of antibiotics could significantly alter the microbiome, anxiety levels, and social behaviour over the long-term.

This most recent study investigated whether P80 and CMC might alter our mental state. The team added CMC and P80 to the drinking water of recipients for 12 weeks. They then measured the changes in the microbiome, behaviour and other physiological changes as well. The results showed that these emulsifiers caused general systemic inflammation, which extended to the brain and to behavioural changes. The researchers published their findings in the journal Scientific Reports.

The impact of emulsifiers

The scientists showed that the emulsifiers did impact good gut bacteria, but in different ways for male and females. They also showed that the changes in behaviour were different between the sexes. Males tended to have an increase in anxiety, where the females tended to have a reduction in social behaviour.

While it is not known how these emulsifiers affect behaviour, it is speculated that the inflammation they produce affects signalling pathways in body tissue and parts of the brain. The gut also contains branches of the vagus nerve, which has a direct link to the brain. The researchers said that more research is needed into this very important area of medicine.

In recent years there have been increase levels of anxiety and mood disorders in our western society. While there are many other factors to the increase of anxiety and mood disorders, such as stress and lifestyle changes, the researchers have questioned if these additives may also be playing a part in this as well.

For now, the researchers recommend that we should really look at how these food additives impact our microbiome and gut bacteria and increase systemic inflammation in the body. It is great to see that science has now showing, beyond a shadow of a doubt, that the microbiome plays a significant role in our overall health. Not just our physical health, but our mental and emotional health as well.

This is why I always recommend health diet and lifestyle changes for every condition I help with. This is also why I promote the use of healthy beneficial bacteria (probiotics) daily in our diet as well. Good health always starts with good diet. Good health always starts with a healthy gut/microbiome as well.

Take care

Regards

Dr Andrew Orr

-Women’s and Men’s Health Expert

-No Stone Left Unturned

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New Year’s Microbiome Reboot & Restore

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Most people often need lose the Christmas and New Years Cheer put on through all the goodies we all consume. This also means our gut and Microbiome and Gut health is out of balance and needs to be rebalanced and restored with beneficial bacteria.

Weed, Repair and Restore

This needs to be done properly and involves weeding out the bad bacteria, repairing the gut mucosa and then restoring the gut and microbiome with beneficial bacteria. These good bacteria also need the right food sources to grow and this is all part of repairing and restoring the microbiome/gut.

Microbiome Reboot and Restore Program

We are offering a Microbiome Reboot and Restore to help you with weight management, help your immune system and also get your gut and digestive system working properly again. It will also help reduce inflammation in those with chronic disease states and help with moods and healthy brain function too. The program also incorporates healthy eating principles.

Let’s start the New Year right by getting your gut health right too.

Please give the clinic staff a call for more details and pricing.

Regards

Dr Andrew Orr

-No Stone Left Unturned

-Women and Men’s Health Advocate

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Red wine protects your teeth and gums and helps your gut health as well

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Researchers have now identified yet another reason why you should keep enjoying a glass of red wine.

While Red wine stains the teeth, a new study says that it might protect your oral health at the same time. The findings were published in the journal of Agricultural and Food Chemistry

The research was led by M. Victoria Moreno-Arribas and colleagues from Instituto de Investigación en Ciencias de la Alimentación in Madrid, and the Department of Health and Genomics at the Center for Advanced Research in Public Health in Valencia.

Polyphenols to the rescue

We already know plenty of reasons to have a nice glass or red and how good it can be for our health. A recent study said that it could help to keep the brain young, and previous research has tied it to hormonal health as well as heart disease prevention. Studies have also shown that drinking a glass of vino each day may help us to live longer as well. But as we always say, alcohol is good for us in moderation, not in excess and should be consumed with food and not on an empty stomach.

While know that red wine has many health benefits, new research from Instituto de Investigación en Ciencias de la Alimentación in Madrid, and the Department of Health and Genomics at the Center for Advanced Research in Public Health in Valencia have revealed red wine may protect against the formation of cavities and against gum disease.

Many of the health benefits of red wine come from its content of polyphenols, which are a series of micronutrients with antioxidant properties. We know that some of these antioxidants, such as resveratrol, can protect against action of free radicals, which play a key role in the cellular aging process.

But polyphenols are also super nutrients which help our microbiome and help with our good gut bacteria. Some polyphenols can be absorbed into the small intestine and there they interact with the gut microbiota and fend off bad gut bacteria that might threaten our health. The research team found that polyphenols found in red wine and grapes could have a similar, protective effect in the mouth, fending off harmful oral bacteria that cause cavities and gum disease.

What the researchers found was that the two red wine polyphenols caffeic acid and p-coumaric acid were most effective at repelling the harmful oral bacteria and preventing them from attaching to healthy tissue. They also found that phenolic metabolites, which are substances formed as the polyphenols start transforming in the mouth, suggested that these small products may in fact be the “active ingredient” associated with the polyphenols’ protective effect.

This is great news for those that like to have a nice glass of red and this research also adds to more health benefits of drinking red wine. But as said before, red wine is an alcoholic beverage and as such it is important not to overdo it either.

What is your friend, in moderation, can also be your enemy in excess. The good thing is now you can enjoy a nice glass of red in moderation and know you are getting many health benefits from it, and also know that your teeth and gut health (microbiome), are being looked after as well.

Regards

Andrew Orr

-No Stone Left Unturned

Women’s and Men’s Health Advocate

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Calling Out The BS Misinformation About Fat Loss

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The reason I am writing this post is that I have had many people contact me about losing weight and getting healthy for their New Year’s resolution. It is that time after all.

But, I have also had some people close to me tell me they have diabetes and other health issues that could significant impact their health and shorten their lives. All of these people have completely preventable diseases and would not be there if their diet and lifestyle was in better shape.

It is that time of year again and it seems to be when most people tend to throw out the healthy habits and adopt some not so healthy ones. Many convince themselves that it is “OK” because it is just for a little while, but the truth is that this altered state of perception often leads into weeks and possibly months of overindulgence and bad eating habits. Then New Year’s Eve comes and people go on the roller coaster guilt trip of needing to be healthy to bring in the New Year.

While it may be OK to eat a few unhealthy things for the day of Christmas, having it every day over the festive season could turn into a nasty habit that could have long term implications on one’s health.  Add in some alcohol everyday and all those bad carbs and the weight (namely fat) can pile on very quickly indeed. This could be especially true if excess fat is stored and the exercise stops and next thing you know that you have a years worth of fat to try and get rid of. Worse still, some people are eating like this every day and not exercising and putting on more inflammatory fat and not realising they are a ticking time bomb. These people then have a lifetime of fat to get rid of and that is not going to be an overnight fix by any means.

So many people always try to convince themselves that a little bit of this, or that, won’t hurt. That is absolute rubbish. Yes, a little bit of this and that won’t hurt if you have reached your optimum weight, got rid of all the bad fat around your body, and reached your health goals. Sure. But if you are already overweight, have excess tummy fat etc, yes, that little bit just set you back big time. Excess fat= inflammation.

Excess fat is also estrogenic and part of the reason obesity also unbalances hormones, causes inflammation in all the cells, decreases fertility, but also puts you at increased risk of many of the cancers we get as humans. We will talk about that in later posts.

Before you start making excuses and trying to plead your fat loss case, you might want to stop for a second and actually listen to some cold hard facts and from a qualified healthcare professional, not your next door neighbour pushing the next multi-level marketed shake diet scam. You need to put down your degrees in Dr Google and tell Dr Google to stick his fat loss advice misinformation where the sun doesn’t shine.

Excess fat and a sedentary lifestyle is going to cut your life short and also lessen your quality of life and increase your risks for other diseases that could cut your life even shorter. It is time to cut the BS (Bullshit) and tell it how it is.

On a daily basis I hear every excuse to why someone hasn’t been able to lose weight, or get their life back on track etc. I have heard it all. Even many of my fertility patients just don’t get that their current fat status is hindering their chances of healthy eggs, health sperm, and healthy embryos and having a healthy baby.

I have heard every excuse from “I go to the gym 2 hours per day and still can’t lose weight”, “But my diet is great and I still can’t lose weight”, “I’ve tried everything and seen everyone and still can’t lose weight” and so many other excuses.

Each time I hear the excuses start, the BS meter starts to go off and I feel the need to call people on their story they are living in. Sure, I get it is hard. Sure, I get the excuses. Sure I get it and understand the story being told to me. But seriously, nobody is going to do this for you.

People just need to take ownership and just admit that they are 100% responsible for their own body and now just need to take on the advice and just do it. You cannot keep blaming someone or something and keep shifting the focus off the one things holding you back, which is your self.

If someone is eating correctly (I mean eating a proper diet, not the one you have been conditioned to believe is healthy by clever marketing for big corporation), then you will burn fat and lose weight. You can’t out train a bad diet and you can’t lose fat if you are getting bad advice.

You won’t lose fat if you aren’t being honest with yourself and having chocolate, treats, biscuits, and drinking alcohol and all the other bad carbs along the way. One biscuit here and one piece of chocolate there, adds up to a crap load of sugar and fat storage in a week. Let’s not forget how alcohol is full of sugar and bad carbs and stores fat too.

Nine times out of ten it isn’t the diet that isn’t working for someone, it is the person not working and not doing things properly. Once that is sorted and proper adjustments made, plus moving the body at the same time, people will always lose that fat. They do when I am helping them.

The other big issue I see is people’s perceptions of what a good healthy diet consists of, or what they have been conditioned to believe is healthy. While this may not necessarily be their fault, once they have been told and don’t do anything about it, then there isn’t anyone to blame but self.

We also have the big issues in this country, and other parts of the world, with all of the unqualified wannabe health coaches (and bloody Dr Google) out there pushing the latest fad and not knowing what the hell they are doing and pushing it onto the unsuspecting masses who lap up the latest quick fix craze. We have also had years of indoctrination by cereal and bad food companies getting us to believe their sales pitch lies to boost their profits and keep us all sick.

Let me tell you one thing. There is no quick fix when it comes to fat loss. There is no magic pill, or magic shake, or magic supplement that is going to melt fat away overnight. People need to get that through their brains and start to be real about their expectations versus the reality of weight/fat loss.

It is called eating well, exercising and changing lifestyles, reconditioning the thought processes and learning to live life and love it at the same time. No shake, or quick fix fad, is ever going to replace a healthy diet and healthy lifestyle.

Those shake diets and quick fix fads only last a short time and while you are doing this and then once you stop, you rebound back to where you are. Don’t get me started on how those shakes etc are full of fillers, full of sugars and lack beneficial real nutrients and live enzymes. They aren’t real foods and they will never be real foods and we shouldn’t need to use them. OMG don’t get me started on what many people think are real foods.

One of the biggest issues with people not being able to lose fat is that their gut flora, or what we now call the Microbiome, is just not balanced and healthy and full of healthy bacteria. You can take multiple supplements and shakes and do copious amounts of exercise, but if your gut flora and Microbiome isn’t balanced and right, then nothing is going to work. If the Microbiome is balanced and healthy, then the rest of the body, the immune system and the mind will be healthy too.

Recolonising the Microbiome and balancing the gut flora is something I always start with when people are wanting to get healthy, and or lose fat. It is an absolute must to be able to reduce inflammation, get the digestion working properly, restoring the immune system, restoring optimum brain function, restore fertility and getting the body burning fat properly. Without getting the gut function working properly, nothing else will function properly either

You are all probably wondering why I use the word fat loss, instead of weight loss. That is because weight loss is not the goal to a healthy body. Fat loss is the goal. It is very easy to make someone lose weight, but the problem with most weight loss systems is that they make you lose muscle and body mass, not burn fat. So people lose the weight on the scales and the fat is left behind and then they rebound. It also leaves you a lighter person full of bad fat and full of inflammation that is still causing you to be unhealthy and have an increased risk of disease. You just become a fat skinny person and that isn’t good either.

We need to redefine the model of thinking around weight loss and start to re-educate people that we need fat loss to help the body become healthy. We also need to have a healthy Microbiome and healthy digestive system to achieve optimum health too. So no matter what your disease state is, your health goal is, or what you need to achieve to get your body back into optimum shape, gut health and a healthy Microbiome should be first and foremost.

Whether you want to lose fat, or recover from a disease state, or have a baby, fat loss and a healthy Microbiome are the integral key that you need to use to unlock your health and New Years goal. If you want to do fat loss properly, then book into a properly trained healthcare professional like myself, or a nutritionist and get your life and health back on track this New Year.

I know sometimes this may sound a little harsh, but it is from a place of caring and a place of wanting to give people the facts. We all need a wakeup call every now and then and sometimes there is no other way to do it but say it how it is. It is time to call people on their BS misinformation and excuses and let’s get the facts out there about what it takes to be healthy and what it takes to lose fat properly too.

Take care and here’s to good health this year

Andrew Orr

-Women’s & Men’s Health Advocate

-No Stone Left Unturned