Being Overweight, or Underweight Can Adversely Affect Fertility

Posted on October 13, 2019October 13, 2019 by Andrew Orr

It is important to have healthy weight and waist size when trying to conceive. It is know that being underweight, or underweight can adversely affect fertility.

Healthy Waist Size

Healthy waist range for a woman is 80cm (from the belly button around) Healthy waist range for a man is 94cm (from the belly button around)

If a woman’s waist size is about 88cm and a man’s waist size if above 102cm then they are in what we call “metabolic syndrome”

Metabolic Syndrome

Metabolic syndrome increases their chances of the following:

diabetes
heart disease
depression
gynaecological conditions (PCOS, endometriosis etc)
sperm issues,
egg quality issues
reproductive issues,
increased miscarriage
increased risk of certain cancers
infertility

Excess body fat (now known as obestrogens) can disrupt hormones and fertility and can have a negative effect on egg and sperm quality.

Similarly being underweight and low body fat can affect fertility outcomes too.

Body fat has a regulatory role in reproduction

Body fat has a regulatory role in reproduction and a moderate loss of fat, from 10% to 15% below normal weight for height, may delay the menstrual cycle, completely stop the menses altogether and inhibit ovulation. Both dieting and excessive exercise can reduce body fat below the minimum amount and lead to infertility. But this is reversible with weight gain, increased body fat and reduction of intensive exercise, or both.

A moderate reduction in body fat, not just weight, for those overweight, can increase fertility and chances of pregnancy exponentially.

Similarly an increase in body fat for those that are underweight, and who don’t have enough body fat, can increase their fertility and chances of pregnancy as well.

This goes for men too. Increased body fat, or not enough body fat can affect hormone production and fertility and can affect sperm quality and sperm production.

The importance of preconception care

This is why preconception care and healthy screening and weight and waist management is so important before trying to conceive. This should also be a part of any fertility program and is definitely part of my fertility program for all couples.

Are you in healthy waist range?

Regards

Andrew Orr

– No Stone Left Unturned

-Master of Reproductive Medicine

-The International Fertility Experts

Lycopene Helps Improve Sperm Quality

Posted on October 13, 2019October 13, 2019 by Andrew Orr

A new research study conducted by the university of Sheffield has shown that supplementation of Lycopene, a compound found in cooked tomatoes, has helped improve the sperm quality in a group of men.

Many studies have examined the role of dietary factors, antioxidants and amino acids and data from randomized controlled trials suggest that antioxidant therapy can improve sperm quality.

Health benefits of lycopene supplementation have been proposed for a variety of health conditions. This recent study examines whether 14mg of daily lycopene supplementation, for 12 weeks, can help improve sperm motility and sperm morphology in men.

Poor sperm quality

Poor sperm quality is a major contributor to infertility in heterosexual couples, but men are often overlooked and often are unwilling participants in the journey to have a baby. There is no doubt that sperm quality is declining and many couples inability to have a baby is actually coming from the male side of things, not the female side.

It is generally recognized that 50% of fertility issues are related to male sub-fertility and poor quality sperm. Typically, fertility problems in the male manifest themselves as ejaculates containing too few sperm (oligozoospermia), or sperm that swim poorly (asthenozoospermia), or sperm with poor size and shape (teratozoospermia) or a combination of all three.

Factors Affects Sperm Quality

Known factors that affect sperm are – Poor diet, obesity, alcohol, smoking, recreational drugs, steroids, medications, chemicals and environmental factors. There are also genetic and hereditary issues that affect sperm as well.

Women are often driving force behind fertility health

Women are often the ones being very proactive in whatever it takes to have a baby and will take supplements, improve their diet, and look at any way they can to help with conceiving. Unfortunately, getting men to do the same can be like pulling teeth and we need to start educating men of the importance of preconception care prior to having a baby.

Men offered very little advice about sperm health

Unfortunately many fertility clinics and healthcare practitioners in general, are giving very little advice and information around what men can do to improve their sperm. Many healthcare professionals are also only focussing on delivering general advice to highlight the known lifestyle risks for poor sperm quality. More advice around preconception care is needed.

Preconception care for men is a must

There is now lots of research about the importance of preconception care for men and lots of research on the importance of a healthy diet, lifestyle changes and the role of antioxidants and amino acids for sperm health and sperm quality.

This recent study could add to the ways that men can improve their sperm quality and help with the outlook for men with known sperm issues. This recent study could also add to existing research and could also lead to better ways to reduce the damaging impact of modern living on reproductive health. We really do need for all couples to know, that of all infertility cases, at least 50 per cent of the issue is due to male factors and poor quality sperm.

Lycopene increases sperm quality

This is the first ever double-blind randomised controlled trial to assess the impact of giving men a bio-enhanced form of lycopene (called LactoLycopene) to see if it helped with sperm quality. The team from the university of Sheffield discovered that the lycopene supplementation made no significant difference to sperm count and concentrations. However the rapid progressive motile sperm and the sperm with normal morphology increase by around 40% in response to the lactolycopene intervention. Rapid progressive sperm and morphology are the two most important parameters for sperm quality and for increasing chances of fertilisation and pregnancy.

During the 12-week trial half the recipients took LactoLycopene supplements and the other half took identical placebo (dummy pills) every day for 12 weeks. Neither the researchers nor the volunteers knew who was receiving the LactoLycopene treatment and who was receiving the placebo. Sperm and blood samples were collected at the beginning and end of the trial. The researchers were surprised by the improvement in the sperm quality shown by the results. The improvement in morphology and rapid progressive sperm was dramatic after lycopene supplementation.

What are Lycopenes?

Lycopene can be found in some fruits and vegetables, but the main source in the diet is from tomatoes. However, the bioavailability of lycopene from fresh tomatoes is low, but this is enhanced by a special natural processing technique of heating and infusing tomatoes with oil. As such, this study used lactolycopene, the main ingredient of which lycopene is embedded in a special protein mix for enhanced intestinal absorption.

This was the first properly designed and controlled study of the effect of LactoLycopene on semen quality, and it has spurred researchers to want to do more research into lycopene and well as other antioxidants and amino acids that may help with sperm quality. The research also shows the role these antioxidants play in helping inhibit the damaging effects of oxidation and oxidative stress.

Oxidation and Oxidative Stress Damage Sperm

Oxidation and oxidative stress is a known cause of damage to sperm and the sperm DNA. Lycopene is a powerful antioxidant that is potentially inhibiting oxidation and the damage of oxidative stress causes to sperm quality. Researchers believe this antioxidant is the key to improvements in sperm quality seen in this trial and could be an answer to the cause of many male fertility problems. More research is needed and the research team is hoping to embark on a new study as soon as possible.

Final Word

As part of my fertility program all males are educated on the importance of preconception care and about optimum sperm health. All men on my fertility program are given antioxidants and supplements that have been shown to assist with sperm quality and maintain optimum sperm health. Men are 50% of the equation of making a baby and why all men need to be included in any preconception care and any program to assist couples in having a baby.

Regards

Andrew Orr

-No Stone Left Unturned

-Master of Reproductive Medicine

-The International Fertility Experts

Journal Reference:

Elizabeth A. Williams, Madeleine Parker, Aisling Robinson, Sophie Pitt, Allan A. Pacey. A randomized placebo-controlled trial to investigate the effect of lactolycopene on semen quality in healthy males. European Journal of Nutrition, 2019; DOI: 1007/s00394-019-02091-5

The Prevention of Childhood Obesity Must Start Before a Couple Conceives.

Posted on September 7, 2019September 7, 2019 by Andrew Orr

The key to preventing obesity in future generations is to make their parents healthier before they conceive, leading health researchers suggest.

In a series of papers, published in The Lancet Diabetes and Endocrinology, the researchers say that the time before couples conceive represents a missed opportunity to prevent the transmission of obesity risk from one generation to the next. They argue that a new approach is needed to motivate future parents to live a healthier lifestyle.

There is now a wealth of evidence that the risk of obesity and its associated conditions, such as heart disease diabetes and some cancers, could impact the developing baby. In turn, when the child becomes a young adult they may pass the risk of obesity on to their children — it is a vicious cycle.

The nature of this problem is not adequately appreciated. Many young people, whilst appearing outwardly healthy, are nonetheless on a risky path to obesity and chronic disease and more likely to pass this risk to their children, the researchers warn.

Many pregnancies are unplanned, and the special needs of adolescents and young people at this important time are not sufficiently recognised. Far from helping them to prepare and plan for pregnancy and parenthood, many public health programmes assume that their needs are similar to the general population and require no special measures or provisions.

In a comment piece accompanying the research papers, Professor Mark Hanson of the University of Southampton, says an entirely new approach is needed that engages parents-to-be and encourages them to be part of the solution.

Engaging future parents in leading healthier lives will not only promote their health later, but will give their children a healthier start to life.

Getting couples to have a healthier diet and lifestyle and manage weight is all part of my fertility program and something we have always promoted. We know that the health of the parents gets passed onto the offspring and why we are so focussed on helping a couple be the healthiest they can be. So many couples are choosing to overlook the obvious because it is all too hard. Well… so they think.

A moderate weight loss of 10% body fat, or an increase for those underweight, can increase a couples chances of conception by 50%. That is huge.

I have helped and assisted over 12,500 babies into the world, via my fertility program. Part of the fertility program is about preconception care and getting the parents healthy before they try to have a baby. Healthy parents produce healthy babies.

If you do need help have a baby, please call my friendly staff about how the fertility program may assist you in having a baby.

Regards

Andrew Orr

-No Stone Left Unturned

-The International Fertility Experts

Being Overweight, or Underweight, Can Adversely Affect Fertility

Posted on July 25, 2019July 25, 2019 by Andrew Orr

As mentioned in previous posts about fertility and weight, it is important to have healthy weight and waist size when trying to conceive. It is important to address dietary and lifestyle issues in order to be in health weight and waist range before trying to conceive.

Healthy Waist Size

Healthy waist range for a woman is 80cm (from the belly button around)

Healthy waist range for a man is 94cm (from the belly button around)

If a woman’s waist size is about 88cm and a man’s waist size if above 102cm then they are in what we call “metabolic syndrome”

This increases their chances of diabetes, heart disease, depression, gynaecological conditions (PCOS, endometriosis etc), sperm issues, egg quality issues, reproductive issues, increased miscarriage, increased risk of certain cancers and of course…. infertility.

Body fat and how it affects fertility

Excess body fat (now known as obestrogens) can disrupt hormones and fertility and can have a negative effect on egg and sperm quality.

Similarly being underweight and low body fat can affect fertility outcomes too. Body fat has a regulatory role in reproduction and a moderate loss of fat, from 10% to 15% below normal weight for height, may delay the menstrual cycle, completely stop the menses altogether and inhibit ovulation. Both dieting and excessive exercise can reduce body fat below the minimum amount and lead to infertility. But this is reversible with weight gain, increased body fat and reduction of intensive exercise, or both.

A moderate reduction in body fat, not just weight, for those overweight, can increase fertility and chances of pregnancy exponentially. Similarly an increase in body fat for those that are underweight, and who don’t have enough body fat, can increase their fertility and chances of pregnancy as well.

This goes for men too. Increased body fat, or not enough body fat can affect hormone production and fertility and can affect sperm quality and sperm production.

Are you in healthy waist range?

Regards

Dr Andrew Orr

-No Stone Left Unturned

-Master of Reproductive Medicine and Women’s Health Medicine

-Women’s and Men’s Health Advocate

01 Dr Andrew Orr 1

Let’s Talk About Why IVF Cycles Fail

Posted on July 24, 2019September 24, 2019 by Andrew Orr

Let’s talk about why IVF cycles fail because it is a very common question that is asked when a cycle fails. Often there will be no conclusive answer and often when I am asked this, I have to say the old saying “How long is piece of string?”

The reason I say this is that there are so many factors involved with a cycle failing. It could be from following

poor egg quality
poor sperm quality
age of the couple
genetic factors (diagnosed, or undiagnosed)
hereditary issues
DNA and chromosomal issues
a non-receptive endometrium
dietary and lifestyle factors
weight factors (excess or too little weight)
emotional factors, or mood disorders
stress
incorrect hormone therapy
medications
human error
lab errors
many other factors in the IVF process.

I wish it was as easy as putting a sperm and an egg together and it just happening. I know many couples do look at it this way, but there is so much more to the whole process of conception. I know it is often hard to understand, but no google search is going to tell you all of this and you would need years of study to completely understand the whole process. Plus IVF is still only a young form of medicine and it still evolving.

This is why IVFsuccess rates are still relatively low. We just do not have the technology yet to tell us which embryo will go on to become a baby. If we had that, then there would be a much higher, if not near 100% success rate. The reality is that type of technology may never be available, or would be many many years off. We can only hope.

The other thing I explain to couple is that sometimes it is literally the IVF process hindering a couples chances of success, by not having the right protocol, or right team helping them. I could go on and on because there are so many factors that could affect a cycle and someones chances of conceiving. This is why I use the term “How long is a piece of string?”

This is why I do what I do and explain all of this and more to all my patients as part of my fertility program. I am literally there to hold their hands every step of the way and explain everything in detail each step of the way as well. I will always make sure everything is done properly and even go into bat for them and step on toes if I have too. My patient’s come first always.

What is required for a successful pregnancy?

At least three things are required for a successful pregnancy during in an vitro fertilization (IVF) cycle:

a healthy embryo
a receptive endometrium
careful transfer at the proper time in the cycle

There are things other things such as the right diet and right nutrients and right emotional state for the couples and proper preconception care, but for now I am just talking about a successful embryo transfer on a medical level. Firstly I will discuss the IVF process.

IVF has improved significantly in its almost 40-year history. Different types of hormone and fertility drugs have been developed that are easier to administer and are associated with an improved safety profile. In addition, numerous stimulation protocols are available that allow us to individually tailor treatments. For example, ultrasound-guided embryo transfer using soft catheters and embryo glue (enzyme to assist implantation) has also helped with ensuring better placement of the embryo, without trauma to the endometrium, but very few clinics are actually doing this. Tests can also be used to evaluate the receptivity of the endometrium in order to determine the best time to schedule the transfer.

Despite all these improvements, however, implantation and pregnancy rates with IVF only slowly increase year after year.

Achieving Implantation-The hardest step

The rate-limiting step of IVF is implantation. It requires the proper interaction of a healthy embryo and a receptive endometrium. It often fails due to problems with the embryos. The genetic health of the embryo depends on both its inherited genetic material and on the errors and repairs during the cell divisions.

A chromosomally abnormal (anuploidy) embryo is unlikely to implant, and when it does it is likely to be lost early on. Many embryos that are transferred have chromosomal abnormalities, even if they look fine on the outside, or are classified as being the best grade prior to transfer. We need people to understand that just because and embryo has reached Blastocyst, or Morella stage and it looks like a good quality embryo from the outside, it does not mean that the inside and the chromosomes inside the embryo are OK. Not every fertilised egg will result in a genetically sound embryo that will go on to become a baby.

DNA & Chromosomal When Sperm and Egg Combine

We also need people to realise that an embryo is made up the genetic material of two people and that requires the sperm to be healthy both outwardly, but also chromosomally, and this can change with each batch of sperm ejaculated. Sperm quality and the viability of sperm changes and just because something was “OK” last cycle, or two years ago, or last month, or last week, does not mean that it is OK now.

Unfortunately people need to face the reality of what happens with the body and reproduction. The health of the sperm is also reflected in the health and lifestyle and age of the male too. Unhealthy males produce unhealthy sperm and higher levels or sperm with chromosomal abnormalities and damage to the DNA. Unless you are testing every batch of sperm for DNA and chromosomal abnormalities, you aren’t going to see this and even then, testing can only see so much.

A healthy embryo (Euploidy embryo) also requires a female to be healthy and her eggs to be health chromosomally and on a DNA level. It also requires a healthy male for his sperm quality to be healthy on a DNA levels as well. Egg and sperm quality is also related to age, diet, lifestyle, environment, and exposure to environmental disruptors, weight, body fat, stress and so many other factors.

We need people to be aware of this. Then when you put two unhealthy people’s genetic and reproductive material together, there is a high likelihood that it will produce higher numbers of abnormal embryos, and sometimes it can be all of them. It all depends on the health of the sperm and health of the eggs at time of fertilisation. Even then we can still have random errors in chromosomes and DNA and this then produces faulty embryos. Again this is a hard process to explain and again Dr Google isn’t going to tell you this.

Pre-implantation Genetic Diagnosis/Screening (PGD/PGS)

Various methods of genetic testing of embryos have been evaluated in past decades. During the early days of PGD/PGD many embryos were lost in this form of screening. Today it is more routine and more perfected. One can test the chromosome content of the polar bodies, but a cleavage-stage embryo (day 3 of development) or a blastocyst-stage embryo can be evaluated as well. In addition, various techniques are available for assessing the chromosomes. There are also new testing and new technologies that have addressed the shortcomings of these earlier tests.

The authors of a recent systematic review concluded that comprehensive genetic screening of embryos using day 5 blastocyst biopsy is associated with increased implantation and pregnancy rates. In addition, this technology appears to be a good tool to limit the number of embryos transferred. But embryos can still be tested early on in their development, with good results, too.

Most experts recommend genetic testing of embryos in women with advanced reproductive age, recurrent implantation failure, recurrent pregnancy loss, or severe male factor infertility/DNA issues. This then gives a greater probability of transferring a chromosomally normal embryo and having a higher chance of implantation and pregnancy occurring. But even a chromosomally normal embryos doesn’t ensure a pregnancy. This is often the hardest thing for people to get their heads around. To be honest, much of this comes down to luck and is really in the hands of the gods. Again this is often not told to people and no google search is going to tell you this either.

Preconception care increases chances of conceiving

But what you can do to ensure healthy egg quality, healthy sperm quality, healthy embryo quality, healthy uterine lining, decreases stress levels, optimal health at time of transfer etc, is doing proper preconception care as part of proper fertility program. There is now growing evidence that the health of both parents before and at the time of conception influences the chances of conceiving and the short and long term health of the future offspring. (9,10,11,12,13,14,15)

This is why I offer couples a program to go over everything they need to know and everything the need to do prior to trying to conceive or trying to embark on the next IVF cycle. It is about getting the couple as healthy as possible and their bodies as ready as possible to give them the best chances of success. I always explain to people that preparing for an IVF cycle is like preparing for a marathon. If you do the work and get the body ready, it gives you a better chance of making it to the finish line.

If you are having trouble falling pregnant, or are having failed IVF cycle, then give my clinic a call and find out more about how my fertility program may be able to assist you achieving success of having a baby. So far my program has helped over 12,500 plus babies into the world and counting. It doesn’t matter if you are starting the journey, or well on your way into the journey or trying to have a baby. You can also do a meet and greet appointment to find out more about the fertility program before you commit to the whole program.

Take care

Regards

Andrew Orr

-No Stone Left Unturned

-Master of Reproductive Medicine and Women’s Health Medicine

-Women’s and Men’s Health Advocate

References

Mains L, Van Voorhis BJ. Optimizing the technique of embryo transfer. Fertil Steril. 2010;94:785-790. Abstract
Society for Assisted Reproductive Technology. Clinic Summary Report. https://www.sartcorsonline.com/rptCSR_PublicMultYear.aspx?ClinicPKID=0Accessed April 27, 2015.
Staessen C, Platteau P, Van Assche E, et al. Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: a prospective randomized controlled trial. Hum Reprod. 2004;19:2849-2858. Abstract
Mastenbroek S, Twisk M, van Echten-Arends J, et al. In vitro fertilization with preimplantation genetic screening. N Engl J Med. 2007;357:9-17. Abstract
Yang Z, Liu J, Collins GS, et al. Selection of single blastocysts for fresh transfer via standard morphology assessment alone and with array CGH for good prognosis IVF patients: results from a randomized pilot study. Mol Cytogenet. 2012;5:24.
Scott RT Jr, Upham KM, Forman EJ, et al. Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery rates: a randomized controlled trial. Fertil Steril. 2013;100:697-703. Abstract
Forman EJ, Tao X, Ferry KM, et al. Single embryo transfer with comprehensive chromosome screening results in improved ongoing pregnancy rates and decreased miscarriage rates. Hum Reprod. 2012;27:1217-1222. Abstract
Scott RT Jr, Upham KM, Forman EJ, et al. Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial. Fertil Steril. 2013;100:624-630. Abstract
Buck Louis, G. M., et al. (2016). Lifestyle and pregnancy loss in a contemporary cohort of women recruited before conception: The LIFE Study. Fertility and Sterility, 106(1), 180-188. doi: 10.1016/j.fertnstert.2016.03.009
Chiu, Y.-H., Chavarro, J. E., & Souter, I. (2018). Diet and female fertility: doctor, what should I eat? Fertility and Sterility, 110(4), 560-569. https://doi.org/10.1016/j.fertnstert.2018.05.027
Day, J., et al. (2016). Influence of paternal preconception exposures on their offspring: through epigenetics to phenotype. American Journal of Stem Cells, 5(1), 11-18
Homan, G. F., Davies, M. J., & Norman, R. J. (2007). The impact of lifestyle factors on reproductive performance in the general population and those undergoing infertility treatment: a review. Human Reproduction Update, 13(3), 209-223.
Nassan, F. L., et al. (2018). Diet and men’s fertility: does diet affect sperm quality? Fertility and Sterility, 110(4), 570-577. https://doi.org/10.1016/j.fertnstert.2018.05.025
Salas-Huetos, A., et al. (2017). Dietary patterns, foods and nutrients in male fertility parameters and fecundability: a systematic review of observational studies. Human Reproduction Update, 23(4), 371-389. doi: 10.1093/humupd/dmx006
Sharma, R., et al. (2013). Lifestyle factors and reproductive health: taking control of your fertility. [Review]. Reprod Biol Endocrinol, 11(66), 1477-7827.

AMH Levels Alone Are Not Indicative of Ovarian Reserve

Posted on May 21, 2019September 5, 2021 by Andrew Orr

One of my biggest bug bares is having so called specialists tell women that AMH (Anti Mullerian Hormone) levels alone are indicative of their ovarian reserve and having them freak out that they now have little, or no eggs left. Nothing could be further from the truth.

AMH levels alone ‘are not’ indicative of ovarian reserve. There is no test on this planet that can tell you how many eggs you have left. There never has been and there will probably never will be.

AMH levels are not a definitive diagnosis for ovarian reserve and their predictive value alone is very questionable. It just gives a ‘rough’ guide that someone may be a poor responder to Assisted Reproductive Therapies (ART) and that is it. Even then, you will often see women with low AMH levels still producing 5-8 eggs a cycle many times while doing IVF etc.

What has inspired my to talk about this, is that last year I had a friend come to see me and she told me she couldn’t have children because she had no eggs left. I found this quite disturbing and continued to ask how she had come to this conclusion.

What was most disturbing is that her whole basis for not being able to have children, was based around the fact that some ….ummmm… and I can’t really voice it any other way… but some “A-Hole” specialist had told her she can’t have children because she had low AMH levels.

No other investigations, no trial of IVF to see if she can respond and get eggs, just one lousy blood test.

This is so disgusting and such BS, they I couldn’t contain myself and had to sit this poor woman down and tell her the facts. Worse still this was from a Fertility Specialist who basically calls himself God and believes he is the best specialist here in the city where I live.

This idiot has basically had someone believe they cannot have children based on one single blood test. This is the sort of thing I see everyday and it shouldn’t happen. The saddest part of this story is that this person is no longer with us and tragically lost her life in a car accident. She never got the opportunity to try and have children all based on some egotistical horrible man who has no idea around the facts about fertility.

I always talk about this subject to other healthcare practitioners and as part of my education in my seminars. AMH alone “Is Not”… repeat “Is Not” indicative of ovarian reserve and nobody can tell you how many eggs you have left anyway. It is utter BS.

To get an “Idea” and I mean a “rough idea” of how well you may respond to producing eggs, AMH levels give us a “rough idea” or a pointer to “maybe” how many eggs you may have left, or if you will respond to fertility drugs. It is not a definitive diagnosis on its own.

To get a more accurate picture of Ovarian Reserve, there also needs to be other tests factored in too. All of these things I discuss when I evaluate someone as part of my fertility program and their initial consultation. Then after these levels and a special test is performed for 5 days, then we evaluate all these factors to basically give a rough idea how well a person will respond to produce eggs. Again this is not an exact, or not precise.

Then if it does look like the person is a poor responder, we put them through a stimulated cycle (basically an IVF cycle) and follicle track (check to see if they produce eggs and how many). Then we can truly evaluate a person for ovarian reserve.

But even if you do have low AMH levels, it does not mean you have a limited number of eggs. It means you might be a poor responder and not produce as many eggs. That is all.

High AMH levels are indicative of PCO/PCOS however and could also be signs of a granulosa cell carcinoma (which is what the test was originally designed to detect)

I know women with AMH levels less than 1 ( <1) still producing 5-7 eggs per IVF cycle, then go onto have a child, or several children with low levels like this.

Yet based on this rude, arrogant, obnoxious specialists evaluation, he would have told women with low AMH levels they can’t have children and many of them may have given up, despite the fact that they may have actually been able to have children. This makes me so upset.

AMH levels only give us a rough idea of how you will respond to fertility treatments and how many eggs you may produce. It is an estimate, or should I say “Guess-timate”

I see so many women come to see me who are freaking out after getting low AMH levels and then being told they have little, or no chance of conceiving, when actual fact they might.

Many of these ladies are also Dr Googling too, which is also spreading BS about AMH levels, just through ignorance and perception and lack of understanding of what these levels actually mean.

As someone who has been awarded a Master of Reproductive Medicine and Master of Women’s Health Medicine. please let me tell you that AMH levels only give us a small, inaccurate insight into what is going on in the body.

AMH levels are not a diagnostic tool on its own and it is never meant to be a diagnostic on its own. There are many other tests that need to be done first and along side this to come to a conclusion of low ovarian reserve, or being a poor responder. Sure, some women may have low AMH levels and after all the testing, we actually do find out they are a poor responder, but not all women will be poor responders.

I hope this story helps those who might have been given the same diagnosis my late friend was given. This is why everyone should get a second opinion, or a third, or even a 5th, when it comes to fertility treatment.

The fertility profession is not well regulated and there are a lot of underqualified people out there saying they are fertility specialists, when they are not. There are also a lot of “A-Holes” with no bedside manner out there and telling people lots of things that just aren’t true as well.

Sorry for having to use some swear words, but as someone with a Masters of Reproductive Medicine & Women’s Health Medicine, and who knows the facts, I need for everyone to be aware of this information.

Take care everyone and I’m here to be a voice for anyone wanting have a baby and I’m here to keep the bastards honest as well.

Regards

Andrew Orr

-Women’s and Men’s Health Advocate

-No Stone Left Unturned

Endometriosis DOES NOT Always Cause Infertility

Posted on March 4, 2019September 9, 2019 by Andrew Orr

Many women are led to believe that if they are diagnosed with endometriosis, that they will be infertile. The one thing I do want all women to know is that Endometriosis DOES NOT always cause infertility.

Over the years I have helped over 12,500 plus babies into the world and many of the women who went on to have these babies had endometriosis.

I have had women who have been diagnosed with endometriosis being told that they cannot fall pregnant, based on the diagnosis and AMH (Anti-Mullerean Hormone) levels alone, and no other fertility investigations. This is disgusting and should never happen. It is so sad hearing things like this and women believing they are infertile and cannot have a baby, when it fact they actually may be able to.

Endometriosis can make it harder to fall pregnant

While having endometriosis can increase your chances of having fertility issues (about 50%), it does not mean you are infertile. To be honest the word infertility is often wrongly uses. Unless you have absolutely infertility and have been diagnosed with a condition that would render you infertile, then we should really be using the word subfertility. Subfertility is a better word to use for those that may be experiencing difficulty falling pregnant, but may need assistance of some come.

Biology 101 tells us that it takes two people to make a baby

Let’s not forget that just because you have endometriosis, it does not mean that the fertility issue falls solely with you. Men are just as big an issue when it comes to fertility issues and could be the bigger part in you not being able to fall. The problem is that many fertility clinics will solely focus on the women because she has a diagnosed condition and this is wrong. Many times I have seen a women with endometriosis blamed as the main cause of the fertility issue, when in fact it is actually the man’s sperm that is at fault. Please remember this. Biology 101 tells us that it takes a sperm and an egg to have a baby, not just an egg.

Endometriosis can make it harder to fall pregnant and can affect egg quality, fertilisation and implantation, due to the resulting inflammation from the disease. But this is where it gets a bit tricky.

Pregnancy rates are not necessarily related to the extent of the disease

It isn’t always about the amount of the disease either. We know that pain levels and the associated symptoms of endometriosis are not related to the extent of the disease. I will address this in one of the other facts posts sometime in the future. The hard thing is that sometimes stage 4 endometriosis sufferers, with lots of the active disease, will have not issues falling pregnant at all. Meanwhile a woman with stage 1, or minimal disease, may have lots of issues falling.

Then we have the women who are having issues falling pregnant and will not even know that they have endometriosis and then it is found as part of fertility investigations, via a laparoscopy. Just remember that a significant portion of women with endometriosis are asymptomatic (meaning no symptoms).

Like I always say to my patients, Endometriosis can make it harder to fall, but having the disease does not mean that you are automatically infertile, or will have trouble conceiving. This is why it is important to see someone who specialises in Fertility, not just a regular OB/GYN or a GP, and also specialises in the area of endometriosis.

Fertility Program

If you are having issues falling pregnant, please give my clinic a call and find out how my fertility program may be able to assist you. I can help you and assist you in receiving the proper fertility evaluation and investigations you should be getting. This is for the couple, not just the woman. Like I mentioned before, my multi-modality fertility program has helped and assisted over 12,500 babies into the world and it may be able to help you too.

Take care

Regards

Andrew Orr

-No Stone Left Unturned

-Women’s and Men’s Health Advocate

-The International Fertility Experts

-The Endometriosis Experts

The Importance of Following Through With Advice, Treatments & Change

Posted on February 19, 2019September 9, 2019 by Andrew Orr

I see so many people who have been ‘missed’ and ‘dismissed’ and who have suffered in silence with their disease state.

But the biggest shame is when those that are offered real help, then do nothing with that advice and continue on the vicious, merry-go-round cycle of their disease.

My motto is “No Stone Left Unturned” and I apply that to every patient that I see. My initial consults are usually 1-2 hours in length and I also do lots of preliminary work prior to see a patient as well. I make sure all my patients are now only sent health appraisal questionnaires, but are also evaluated with mood and stress questionnaires for their mental health too.

I really want to delve into every fine detail of a persons life to see what may be driving their disease state and symptoms. It is to also help with diagnosing those that have not been properly diagnosed either. I then write up a comprehensive report for all my patients, with everything they need to do, the changes they need to make, the medicines they need to take, the investigations and testing they need to have and all their step by step health management moving forward. It really is a matter of ‘No Stone Is Left Unturned’ as I mentioned before.

As I mention in this video blog is that the greatest shame is those that come to get the advice and help and then do nothing with it. Just remember that if you do not change anything, or do the work needed, then nothing changes. The key to real change is actually within you.

If you so need help with a particular health issue, or you just aren’t getting the right answers and care, then please book in a time to see me and let me be your guide to better health and getting your life back to normal.

Let’s Talk About Fertility

Posted on February 19, 2019September 9, 2019 by Andrew Orr

Dr Andrew Orr has an honest and open chat about his years of experience dealing with couples with fertility issues.

Much of it gets back to couples not having the proper testing and investigations, being on the same page, preconception planning, getting healthy, doing the work and the expectations versus reality.

Have a listen to Andrew’s open and honest discussion about a very serious topic.

If you do need help and are struggling with fertility and not having a baby, Andrew can assist you in your journey to becoming parents.

To find out how Dr Andrew Orr’s fertility program, please call his friendly staff to find out more.

Why Iron Deficiency and Anaemia Should Be Take More Seriously

Posted on December 11, 2018September 8, 2019 by Andrew Orr

One of the common things I am seeing in women of all ages is iron deficiency and anaemia. Many women have very low levels of iron and are unaware of the dangers this may pose to their short term, and long term health.

We are also seeing women being hospitalised and seek emergency help due to iron deficiency and anaemia and this highlights that there is inadequate management and detection of a very preventable condition. It also means that many women are not taking this matter seriously enough and often put off seeking screening and then aren’t having their iron levels managed properly.

I need to let all women know that having low iron can be very dangerous. It is something that should not be glossed over, or taken lightly. Iron deficiency can and does cause short term and long term health complications.

Iron deficiency can raise the risk of the following health conditions

Coronary heart disease
Stroke
Osteoporosis
Compromised immune system
Increased risk of infections
Tachycardia
Heart failure
Enlarged heart
Lung problems
Muscle aches and cramps
Restless leg syndrome
Delayed growth and development (mainly in children)

These are just some of the health issues that being low in iron can cause and it very important that we start educating all women and healthcare providers about the importance of iron.

What are the symptoms of Iron Deficiency and Anaemia?

Fatigue
Weakness
Dizziness
Fainting, or feeling of feeling faint
Pale skin
Breathless
Frequent headaches
Palpitations or racing heart
Easily irritated
Difficulty in concentrating
Cracked, or reddened tongue, sore tongue
Loss of appetite
Strange food cravings such as wanting to eat dirt, or clay
Cold hands and feet
Brittle nails
Hair loss
Tingling, or crawling feeling in the legs

Iron deficiency is a very common cause of fatigue and other health issues in women and men, but is more commonly seen in women. Iron deficiency is also the most common cause of anaemia.

What are the causes of Iron Deficiency and Anaemia?

Heavy menstrual bleeds
Endometriosis
Adenomyosis
Fibroids
Polyps
Coeliac disease
Inflammatory Bowel Disease
Stomach or intestinal ulcers
Pregnant and Breast Feeding Women
Certain Cancers
Vegetarians and Vegans
Eating disorders and food restriction
Girls going through puberty
Certain illnesses

Heavy menstrual bleeds and gynaecological condition’s such as Endometriosis, Adenomyosis, Fibroids and Polyps are some of the main causes of iron deficiency and anaemia in women. This is closely followed by dietary inadequacies and food and nutritional restriction.

Many women have undiagnosed gynaecological conditions which are the cause of their iron deficiency and anaemia. Some of these gynaecological conditions will require surgical interventions to be diagnosed properly.

How are Iron Deficiency and Anaemia Diagnosed?

Your healthcare provider can organise routine blood tests to test for iron deficiency and anaemia. These will include the following

Full Blood Count (FBC)
Iron Studies

These tests will provide the following information on :

The Total Iron level in your blood
Ferritin levels
Total iron-binding capacity (TIBC)
Iron saturations levels
The red blood cells size and colour (RBCs)
The white bloods cells (WBCs)
Haemoglobin
Hematocrit ( the percentage of blood volume that is made up of RBCs
Blood platelets

Other tests

There are other tests to check for the cause of iron deficiency and anaemia and these could include stool analysis (check for blood in stool), endoscopy and colonoscopy ( surgical intervention gastrointestinal bleeding) and laparoscopy (key hole surgery for gynaecological conditions)

Treatments for Iron Deficiency and Anaemia

Diet– A healthy diet that is rich in proteins, vegetable and iron rich foods is the best way to ensure your iron levels stay at optimum levels. A proper diet should include leans meats, seafood, nuts, seeds, healthy oils, green leafy vegetables and other coloured vegetables, and moderate fruit intake.

Supplements– Supplements will help to keep iron levels and vitamin B12 levels in optimum ranges. Iron supplements are very much needed if you are vegetarian, or vegan. There is now research to show that women who experience fatigue will benefit from supplemental iron, even if their iron levels and ferritin are within normal range. Those with heavy menstrual cycles, or those whom have inflammatory bowel issue should also be supplementing

NB- All iron supplements should be taken with vitamin C to help with absorption. Many iron supplements also cause constipation and therefore you should get a good one that does not interfere with your bowel habits and is more easily absorbed. Many of the mineral based iron products are not absorbed well and do cause gastrointestinal upset.

I always recommend a specific practitioner only brand to my patients because it is better absorbed, and it does not interfere with the bowel habits.

Iron Infusion– Sometimes when iron gets too low, supplements just will not be enough to get iron levels up to where they should be quick enough. This is where iron infusions can be very effective. Please see my post on when you need to use and iron infusion. (Click here)

Treating the underlying cause of bleeding

Supplements will not help if the cause of the iron deficiency and anaemia is from excessive bleeding. It may help a little, but it will not be enough. Even iron infusions will only be short lasting if you don’t treat the underlying cause of the bleeding issue. Extreme cases may even need a transfusion to get iron levels and blood levels back up to optimum. This is why it is important to screen for underlying gynaecological conditions that can cause heavy and excessive bleeding.

If you are getting low in iron if means there is something wrong and there is a deficiency that needs to be addressed. Please do not take iron deficiency lightly and always be prompt to find the causes and restore optimum levels of iron in the body.

Prevention is a must

Prevention is always the best way to treat any health condition and this goes for iron deficiency as well. Ensuring you eat a healthy diet with iron rich diet is a great start. As said before, vegetarians and vegans are going to have to supplement and work really hard with their diet to ensure they get adequate iron. Even then it can still be hard as plant based foods just do not have the iron levels that meats, eggs and seafood’s have.

Make sure you also have lots of vitamin C in your diet to help with iron absorption and it is a good idea to supplement with vitamin C to ensure you get the right daily intake.

Final Word

If you do think you might be low in iron or have anaemia, please make sure you talk to your doctor, or your healthcare practitioner. Please do not supplement with iron without checking your levels first. Having too much iron can be dangerous and you also need to make sure you do not have hereditary high iron (haemochromatosis), which can present with the same symptoms as low iron.

If you are found to be low in iron, then please make sure you take prompt action to restore your iron levels and also make sure you are screened as to why you are low in iron in the first place.

Iron deficiency and Anaemia can be very serious and should never be taken lightly. Please always consult with your doctor, specialist, or healthcare practitioner for the most effective ways to keep your iron levels in healthy ranges.

Take care

Regards

Andrew Orr

-No Stone Left Unturned

-Women’s and Men’s Health Advocate

-The Women’s Health Experts