Dr Andrew Orr’s clinic has a Pre-Fertility Program Meet and Greet appointment available for those thinking of joining the Fertility Program and who just want to meet Dr Orr first and find out a bit more about the program. The meet and greet appointments gives couples, or individuals, a chance to meet and greet with Dr Orr and have a quick look over their basic health history, as well as have the program explained to them. Patients can go straight on the program and bypass the meet and greet if they wish to do so. For more details about the Fertility Program (click link)
Couples attending the meet and greet appointment are sent out the pre-fertility program questionnaire, and this must be sent back prior to the appointment. The appointments can be in person, or online for those living out of our local area, or who are international. You will be given more comprehensive questionnaires upon signing up to the program.
Please note that the introductory meet and greet appointment is ‘half an hour only’ and ‘is not’ the initial appointment for Dr Andrew Orr’s Fertility Program. This means that you will not receive any fertility supplements, special fertility formulas, medical advice or referrals during this appointment. Please also note that Medicare and private health rebates are not available for this appointment. (The cost of the appointment is $120).
Dr Andrew Orr’s fertility program has assisted and helped over 12,500 babies into the world and this number is increasing every week. He has helped couples locally, interstate and internationally and has had many media stories about his success with couples.
Dr Andrew Orr has been awarded a Masters of Reproductive Medicine and a Masters of Women’s Health Medicine through the faculty of medicine at UNSW. He is also a Doctor of Traditional Chinese Medicine, a Nutritionist, a Natural Medicine practitioner, a qualified Chef and more. With his wide range of qualifications and over 20 years experience in assisting fertility and gynaecological issues, he is able to bring you a truly integrative multi-modality approach to assisting couples with fertility and having a baby. His motto is “No Stone Left Unturned” and the media have named him “The Brisbane Baby Maker”
If you aren’t getting the answers you need and the help you need, then Dr Orr’s Fertility Program could just be the answer you are looking for. The Meet and Greet appointments allow you to see if this program will be what you would like to do. If you would like more information about this, please do not hesitate to call Dr Orr’s clinic, ask us to email you an information pack.
We look forward to helping you on your journey to have a baby, just as we have helped over 12,500 (plus) couples bring their babies into the world too.
Dr Andrew Orr’s Team
-No Stone Left Unturned
-Meet and Greet Appointments
These are some of the main Facts about PCOS
Dr Andrew Orr
-No Stone Left Unturned
-Women and Men’s Health Advocate
The word “Barren” comes originates from the French word ‘Brehaigne’, which means not producing, incapable of producing offspring, infertility, infertile; sterile.
Sounds terrible doesn’t it?
Fortunately very few women are ‘sterile’ and the word “infertility” is often misused in our modern society. Nobody is truly infertile, unless they actually have reproductive organs missing, or have genetic abnormalities that will actually prevent conception from happening etc. When a couple is having trouble conceiving, we should really use the word “sub-fertility” instead of “infertility”
The problem with talking fertility, sub-fertility, or infertility is that we often reference, target, or even blame the woman. Yes, women are often the blame of not being able to conceive a child and therefore the myth of the barren woman still runs deep and is very much in existence and kept alive by all concerned today in our modern world.
But is conception and the ability to conceive a child inherently the fault, or responsibility of the woman?
The answer to that is “No!”, but there is still this expectation, or focus, that not being able to conceive all falls back on a woman. Sometimes women actually wrongly blame themselves, or wrongly take on that responsibility too. Some women will even take on that burden, to protect a partner, who may actually be the main issue. Then we now have an area of medicine that has its focus as being the woman, because women are the primary driving force for wanting to have a child. Hence the vicious cycle continues in this terrible loop and then many, practitioners included, buy into the myth of the barren woman and so the cycle continues over and over again.
Well, I am here to tell you that women are not the only part of having a child and that men play just as big a part when it comes to fertility issues and not being able to conceive.
No matter what you get sold, or what BS (bullshit) you are sold, while pulling on your ‘I need a baby heartstrings’, to make you part with your hard earned money, the fact remains, and will always remain, that it takes a sperm and an egg to make a baby. That is basic biology 101 and no matter what someone tries to tell you, sperm quality is just as important as egg quality in this equation.
Every day I see practitioners, both medical and in complementary medicine, focussing in on women as the primary focus of fertility and actually feeding the myth of the barren women by their very actions. Many times the men are overlooked, or ignored, or completely disregarded in the fertility equation. Not only is this unethical, to just treat and focus on the women when it comes to fertility treatment, but it is highly negligent as well. Men are not born with an inherent right to automatically be able to conceive and worse still, the male sperm levels have fallen by as much as 60% in the last 70 years, with sperm quality levels said to be dropping at an alarming rate.
So why is the focus, the burden, the guilt and the whole emotional baby roller coaster left solely to women?
Well, I have explained that practitioners are to blame, the fertility profession is to blame, society is to blame, guilt is to blame and last of all men are a big part of the issue too.
Men are often to reluctant passengers in the fertility journey and are often very happy to bury their heads in the sand and pass the responsibility of not being able to conceive onto a woman. Then many men are told their sperm is fine, when in fact it is far from being fine.
Over 50% of fertility issues are related to male factors and up to 85% of miscarriage issues may be related to male chromosomal, or DNA issues related to sperm. As I said before, research has now shown that the male sperm quality has fallen by up to 60% over the last 70 years and is actually on the decline. Men are often the bigger part of the fertility picture and it isn’t just the woman at all.
Semen analysis parameters are based on what is needed for Assisted Reproduction (IVF, IUI, ICSI) , not based on what is needed for natural conception and this is where some of the biggest issues lay. Misinterpretation of semen analysis and misinterpretation of parameters have many men believing they have OK sperm, when in fact it is far from being OK. With modern procedures such as ICSI, we only need a few single sperm to be able to fertilise eggs and this can still be considered ok, because at least there was some sperm to fertilise the egg in the first place. A few single sperm, or a few hundred sperm, or even a few thousand sperm is not OK when it comes to natural conception. We actually need a few hundred million sperm for it to be OK and even then they need to be motile and they need to be swimming properly (rapid progressive) and actually be of good shape (morphology)
While a semen analysis is often the first part of male fertility evaluation, it is also very limited. While we can look at morphology, motility, concentration, count etc, it does not tell us about the actual quality of the sperm inside. Many sperm may look ‘OK’ via a semen analysis, but inside their DNA integrity is poor and there are high amounts of DNA fragmentation and this can only be measured by a DNA fragmentation analysis. Even then, each time a man ejaculates, the quality of the sperm will be different and can differ by up to 20% in each ejaculate.
We also know that what a man eats, drinks and even his physical and emotional health will affect his sperm quality and that a man’s physical, dietary and emotional health can be passed onto his offspring through the sperm. This is why it is important for a man to get his physical and dietary and emotional health in check way before he tries to conceive a child with his partner.
We always say that the healthier a man is, the healthier his sperm is and the healthier the woman is, the healthier her eggs will be also. A healthy man and a health woman produce healthy babies.
I have been assisting couples with fertility and pregnancy for over 20 plus years now, and helped over 12,500 plus babies into the world, and I can tell you that conception is not just about the woman. It gets back to basic biology 101 that it takes a sperm and an egg to have a baby. Even when couples are having issues trying to conceive, or doing IVF, or however they are trying to conceive, there will be some issue on the man’s side and the woman’s side. Unless there is absolute infertility on one side, or the other, there will always be a bit of both the man and woman to work on to assist in being able to conceive.
While the myth of the barren woman runs deep in society, fertility clinics and through the guilt handed down from their fellow sisters and mothers, fertility issues and the right to be able to conceive ‘does not’ fall solely into the hands of a woman, far from it. Men are an equal part in the fertility equation and men need be held just as accountable when it comes to trying to have a baby, or if there are difficulties in conceiving. No matter what anyone tells you, a man needs to be part of treatment, management and support of the journey to have a baby. This is a big part in my multi-modality fertility program being so successful in assisting over 12,500 babies into the world. Fertility isn’t just the responsibility of the woman, it is the responsibility of the man as well and I make sure both the man and the woman are properly investigated, clinically managed and helped with treatments as well.
Dr Andrew Orr
-No Stone Left Unturned
-The Brisbane Baby Maker
Men, it is time to eat more nuts, to help your…. ummm… NUTS!
But this isn’t just about your family jewels, this is about helping with what they produce and helping you carry on your family tree. A diet rich in nuts has been shown to improve sperm count, motility, morphology and sperm DNA.
Recent research published in the European Society of Human Reproduction and Embryology (July 4th 2018) has shown the men that regularly eat nuts have improved sperm quality and function and less DNA fragmentation in their sperm.
In many forms of traditional medicines, foods and the shapes of foods, often correlate to an organ in the human body. To give you an example, walnuts look like a lung and they also look like a brain. There are now research papers to show that walnuts may assist with brain function and help with lung function as well.
Many of the foods we eat may also assist fertility. Many of these foods may look like a reproductive organ, or contain seeds in them. Fruits such as dragon fruit and kiwi fruit look like the shape of a testicle, or an ovary and have seed in them, which traditional medicines often say are good for the seed (meaning eggs and sperm on a fertility level)
Hence it is no surprise that nuts, can help with… ummm… well…. a man’s nuts (reproductive organs)
This new research showed that the inclusion of mixed nuts (almonds, hazelnuts and walnuts) in a regular diet significantly improves the quality and function of human sperm, according to results of a randomized trial which measured conventional semen parameters and molecular changes over a 14-week study period. The findings, say the investigators, ‘support a beneficial role for chronic nut consumption in sperm quality’ and reflect a research need for further male-specific dietary recommendations.
Results firstly found significantly higher levels of sperm count, vitality, motility and morphology in the men randomised to the 60 g/day nut diet than in those following their usual diets free of nuts. Moreover, the subjects in the nut group also showed a significant reduction in their levels of sperm DNA fragmentation, a parameter closely associated with male infertility. Indeed, it was this change in the level of DNA fragmentation in the sperm cells by which the investigators explained, at least in part, the improvement in sperm count, motility and morphology.
Nuts are dense foods containing many antioxidants, omega 3 oils, amino acids and folate. This may explain why nuts are so beneficial to improving sperm quality overall. Antioxidants help with oxidative stress, which can be a big factor in DNA damage to sperm and poor sperm quality. Antioxidants and amino acids help with proper formation of sperm at the cellular stage and help prevent damage to sperm cells and help with repair and formation of the DNA of sperm as well.
There is much more growing evidence through research literature that healthy lifestyle changes such as following a healthy dietary pattern can assist conception. Healthy parents make healthy babies. It takes a sperm and an egg to make a baby and healthy men produce healthy sperm. This is why it is important for not only the woman to be healthy prior to conception, but for the man to be healthy as well. The health of the father is passed onto the child and there is growing evidence to support this now.
When it comes to fertility and trying to have a baby, males need to be an equal part of the equation. Fertility isn’t just a woman’s responsibility and fertility issues are not just related to women.
Dr Andrew Orr
-No Stone Left Unturned
European Society of Human Reproduction and Embryology. “A diet rich in nuts improves sperm count and motility: Improvements associated with better male fertility and explained by a reduction in sperm DNA fragmentation.”
New research published in Human Reproduction, has found that those who follow a “Mediterranean” style diet at least six months before assisted reproductive treatment have a significantly better chance of becoming pregnant and giving birth to a live baby than women who did not.
As part of my Fertility Program, one of the first things I talk to couples about is the importance of a healthy diet that has adequate protein, lots of vegetables, seeds and nuts, healthy oils, adequate water intake, electrolytes and cutting out all the refined carbohydrates that cause inflammation. The hard thing is that I hardly see a couple following those health food principles, with many not even really knowing what a health diet is. The diet that I promote is a Primal based diet.
Previous studies have shown that when refined carbohydrates are cut out and replaced with proteins, essential fats and good carbohydrates, such as fruit and vegetables, that the clinical pregnancy rates shot up by 80%. (Fertility & Sterility 2012 Volume 98 issues 3 Page S47)
In this new study, researchers focussed in dietary patterns rather than individual nutrients, food, or food groups. They found that those who ate lean protein, more fresh vegetables, fruit, fish and olive oil, had a 70% greater likelihood of achieving a successful pregnancy and birth compared to women who didn’t follow this style of diet.
The research outcomes found that out of the 244 women in the study, 229 women (93.9%) had at least one embryo transferred to their wombs; 138 (56%) had a successful implantation; 104 (42.6%) achieved a clinical pregnancy (one that can be confirmed by ultrasound); and 99 (40.5%) gave birth to a live baby.
The most important message to come from the study is that women attempting to have a baby should be encouraged to eat a healthy diet, such as a Mediterranean style diet, because it may help increase the chances of successful pregnancy and successful live birth.
The researchers did note that when it comes to conceiving a baby, diet and lifestyle are just as important for men as for women. Previous studies from the same research group showed that male partners that adhered to the same sort had better semen quality.
A healthy diet is important for all couples prior to trying to conceive and should be a part of any preconception planning by all healthcare practitioners assisting couples with fertility. While this study focussed on improving assisted reproduction pregnancy rates, this style of diet should be adopted by any couple wanting to have a baby and should be implemented at least 6 months prior to conceiving. This is why it is essential for all couples to receive counselling and guidance on the importance of a healthy diet and having a healthy lifestyle as well. This is a foundation of my fertility program that has helped over 12,500 babies into the world and continues to help many more couples reach their goal of becoming parents.
Dr Andrew Orr
-No Stone Left Unturned
A new study shows that zinc deficiency can negatively affect the early stages of egg development, reducing the ability of the egg cells to divide and be fertilised. This may affect fertility “months” in the future and why preconception planning is so important for a couple. The researchers will be presenting their results at the American Physiological Society annual meeting at Experimental Biology 2018 in San Diego.
Millions of couples around the world struggle with fertility issues and the ability to conceive a child. While there are many factors that can make conception difficult, ovulation disorders and sperm issues are a leading cause of couples not being able to conceive. Researchers are finally looking into how vitamins, amino acids and micronutrients affect fertility and in particular the early stages of egg development.
The availability of micronutrients, through diet, amino acids, antioxidants and vitamin supplements, in the ovarian environment and their influence on the development, viability and quality of egg cells is now the focus of a growing area of research. Sperm also need micronutrients, antioxidants, vitamins and nutrients for optimal growth and development too. This is nothing new to me as this is something I have always focussed on for many years as part my fertility program and as a part of preconception planning and making sure that the couple are in optimal health before trying to conceive.
In human and mammals, the ovary is made up of thousands of structures called follicles, which consist of one oocyte surrounded by layers of support cells, known as somatic cells. At puberty, the body starts to prepare groups of oocytes for maturation, ovulation and fertilization. While a female grows groups of oocytes, which begin to mature each month, only one will be ovulated and have the chance of being fertilized. Many things can influence whether an oocyte will mature correctly and the go on to one day be ovulated, including the presence of sufficient levels of certain micronutrients. To date this has probably been poorly understood by many.
Scientists have recently found more and more evidence to show that zinc is a key player in oocyte development and have been assessing the effects of zinc on egg development extremely early on in the development and maturation of oocytes.
Previously Fertility research and treatment has primarily focused on the larger follicles, called antral follicles, which respond to signals from the pituitary gland to be ovulated. In humans, preantral follicles have to keep growing for about 90 days before they are ready to ovulate. This is why it is important to focus on egg and sperm quality months before conception is to take place, because this is when both egg and sperm are still growing and maturing and need vital nutrients to develop properly.
In this new research they have examined the smaller preantral follicles, which are still growing and don’t respond to the ovulatory signal yet. Previous studies showed that zinc levels are critical in the antral follicle, but no one had tested the effect of zinc deficiency on preantral follicle growth.
The researchers collected preantral follicles and then matured them in a special cell culture medium. They compared eggs matured in a zinc deficient environment to those grown with normal levels of zinc. The researchers found that preantral zinc deficiency:
- Impaired the egg cell’s ability to properly divide (meiosis), which is a necessary step before successful fertilization can occur.
- Led to smaller and more immature egg cells early in development
- Hindered and disrupted growth of the cells
- Caused problems with development of somatic cells and elevated certain cell markers.
The new research shows that zinc plays an important role in oocyte growth at an earlier stage than previously investigated, which is during development and before division. The research also showed why preconception nutrients are needed months before the eggs fully develop to give the best outcomes for a healthy pregnancy.
It is estimated that about 17 percent of the global population may be deficient in zinc, due to poor dietary intake their diet. But the estimate may not include cases of marginal zinc deficiency, where people may be getting zinc in their diet, but not enough for their recommended levels. People that are more susceptible to zinc deficiency are those with dietary and disease factors such as irritable bowel syndrome, Crohn’s disease, gastrointestinal disorders and liver disease, those with eating disorders, those with certain dietary restrictions, such as vegetarians or vegans, who may not then be taking supplemental zinc.
Preconception planning, care and management is so important for a healthy pregnancy to occur and should start months before trying to conceive. This is to ensure that the sperm are in optimal health and quality and also to make sure that the egg quality is optimal and in the best quality it can be as well. This is what I do for all my fertility patients and is a crucial part in the high success of my fertility program that has now helped over 12,500 babies into the world.
Dr Andrew Orr
-No Stone Left Unturned
Consuming just one sweetened soft drink a day reduces a couples’ chances of conceiving by more than 30 per cent, according to new research published in the journal of epidemiology in February 2018.
Men who drink at least one sugary softdrink/soda a day reduce their chances of fathering a child by 33 per cent, research has found.
Women who drink just one sugar-sweetened softdrink/soda beverage a day are 25 per cent less likely to become pregnant in any given month, the research adds.
Before you think about switching to diet soft drinks, or diet soda, you may want to think again. Studies have shown that diet drinks of any kind are actually worse than the ones containing real sugar. These diet drinks contain aspartame, which then gets converted to phenylalanine in the body. Phenylalanine is toxic and what we use to preserve dead bodies with. It can have a detrimental effect on fertility.
Previous research has also shown that eggs and embryos may fail to thrive in high blood glucose environments. Sugar and highly refined foods has also been linked to erectile dysfunction in men.
The researchers analysed 3,828 women and 1,045 of their male partners, who enrolled in the study between June 2013 and May 2017, and were followed until pregnancy or for up to 12 menstrual cycles. The couples were not using fertility treatments and had only been trying to conceive for six months or less.
The researchers from Boston University found positive associations between intake of sugar-sweetened beverages and lower fertility, which were consistent after controlling for many other factors, including obesity, caffeine intake, alcohol, smoking and overall diet quality.
Couples planning a pregnancy should be looking and lifestyle and diet before trying to conceive and consider limiting their consumption of these beverages, especially because they are also related to other adverse health effects.
In my comprehensive fertility program, diet and lifestyle choices are all covered along with everything a couple needs to conceive. No stone is left unturned with my multi-modality approach to fertility, where everything on a medical level, as well as a complementary medicine level is covered, alongside dietary and lifestyle management. This truly integrative fertility program has helped over 12,500 babies into the world and those numbers are increasing everyday
Dr Andrew Orr
-No Stone Left Unturned
A study published December 19th in the journal Immunity shows that part of the uterine Natural Killer cell population helps to optimize maternal nourishment of the fetus at early stages of development, not hinder it. These Natural Killer Cells have actually been shown to secrete growth promoting factors that can also reverse impaired fetal growth and help prevent miscarriage, not cause it.
For many year now I have had people contact me and trying to kill the killer cells, or treat high natural killer cells, or wipe out these cells that they are being told is causing them to miscarry, or not be able to hold an embryo. For those same amount of years I always said that Natural Killer Cells are meant to be there and the reason they are there is because of inflammation and are doing their job. Now finally, what I have been saying has been proven to be true and now we have an explanation of what these immune cells actually do and the mechanism behind it. They don’t harm the embryo at all. They are there to protect it, nourish it and help it grow.
Natural killer cells are among the most abundant immune cells in the uterus during the first trimester of pregnancy, but their numbers decline substantially after the placenta forms. Up until recently many in the fertility profession have led people to believe that Natural Killer Cells are the cause of all their issues and these new findings may have them eating their words. Not only have women been offered hormones, steroids and the likes that have never been proven to do they say they do, but they not only have major side effects, but could actually be trying to regulate the very thing that is meant to help a pregnancy.
The results of these new findings not only reveal new properties of natural killer cells during early pregnancy, but also point to approaches for therapeutic administration of natural killer cells in order to reverse restricted nourishment within the uterine environment
Acting as our bodies’ frontline defense system, natural killer cells guard against tumors and launch attacks against infections. This is something that I have been trying to explain for years. If natural killer cells are in high amounts, they are there for a reason and that reason needs to be treated, not the high killer cells. There has been much research on how Uterine natural killer cells promote immune balance and the growth of blood vessels in the placenta, having a positive impact on birth weight as well as fetal growth. But until now, it was not clear which subset of natural killer cells in the uterus are responsible for promoting fetal growth, or whether these cells help to optimize fetal nourishment at early developmental stages.
In the new study it was discovered that a specific subset of natural killer cells in the human uterine lining secretes growth-promoting factors, which are involved in wide-ranging developmental processes. This subset of cells made up a smaller proportion of natural killer cells in the uterine lining of patients who experienced recurrent spontaneous miscarriage and reduced implantation (42%) compared to healthy females (81%). These findings suggest that insufficient secretion of growth-promoting factors by a specific subset of natural killer cells may be responsible for restricted fetal development in humans.
The studies also showed that a deficiency in this subset of natural killer cells resulted in severe fetal growth restriction and defective development of the fetal skeletal system. The studies also showed that the transfer of uterine natural killer cells reversed fetal growth impairments. For the purpose of promoting fetal growth in humans, it may be possible to transfer natural killer cells via intravenous infusion or the administration of a vaginal suppository to mothers, avoiding the need for invasive procedures. Moreover, uterus-like natural killer cells are a much safer alternative to many of the methods used in immunotherapy and safer that steroids, or other immunosuppressant’s.
Obviously more study is needed, but these findings are about to turn part of the fertility profession upside down and make it re-evaluate itself
I’ve always said it isn’t the natural killer cells killing off embryos and always said it was from inflammation and inflammatory gynaecological conditions that weren’t being treated. We now know that stress uterine cells are also a big part of the issue too. I always say treat the cause to treat the symptoms and now we know that Natural Killer cells aren’t part of the cause, they are actually there to help.
If you are having troubles not conceiving, or having troubles with miscarriage, it might be time to book in and be a part of my fertility program that has helped over 12,500 babies into the world
Dr Andrew Orr
-No Stone Left Unturned
It is stressed uterine cells and inflammation causing miscarriage and causing the embryo not to implant, not Uterine Natural Killer cells.
For the first time the functions of natural killer cells in the womb have been identified by Researchers at the University of Warwick and University Hospitals Coventry
Although it has long been known that the lining of the womb harbours dynamic uterine natural killer cells, no functions have so far been given to these cells outside of pregnancy.
The researchers have discovered that the uterine natural killer cells remodel and refresh the lining of the womb at the time of embryo implantation. This is the first time a role for uterine natural killer cells in the lining of the womb has been identified outside of pregnancy. The research was published on December 14, 2017.
In addition they discovered that this process isn’t always balanced in each cycle. The natural killer cells perform the role of targeting and clearing inflammatory stressed cells, thereby making space for the implanting embryo. However sometimes not enough of these cells are cleared away and sometimes too many are targeted and removed. Excessive inflammation or insufficient clearance by uterine natural killer cells makes miscarriage more likely.
For many years I have been trying to tell people that they need to stop trying to get rid of the natural killer cells, or reduce their numbers. I have long known that natural killer cells are meant to be in the body and their job is to protect us from infections, bacteria, cancers, tumours and inflammation. If killer cells are in high numbers, it means that there is something wrong and that is what needs to be treated, not the killer cells. But unfortunately, many clinics play on couples emotions and the use of the word “Killer”. So then we get this war on killer cells and people wanting to kill the killer cells because they think it is killing their babies. No matter how hard I have tried to explain it, people just don’t listen and now it is finally great to have the research to back up what I knew all along, plus additional knowledge of how Killer cells actually help with implantation and reducing miscarriage.
The researchers have explained what happens if the natural killer cells cannot do their job properly, or there is inflammation that they haven’t been able to target. They said that a good analogy is Swiss cheese: without holes, the embryo has nowhere to go which will cause implantation failure; but if the holes are too large, the tissue will physically collapse and lead to miscarriage. This imbalance, which may be short-lived or last for multiple cycles, explains the high rate of early pregnancy failure. It really can be a numbers game on how long that cycle could last and why it is important to make sure there are enough natural killer cells there to do their job properly. Without the natural killer cells, there is more chance of inflammation and stressed uterine cells being left behind, which will then lead to higher pregnancy loss and reduced implantation.
The researchers conducted an analysis of 2,111 endometrial biopsies, which is more than had ever been conducted previously. The research team examined the acutely stressed cells in the lining of the womb which generate tissue inflammation. They found that the natural killer cells which are in the womb perform the important function of selectively targeting and eliminating acutely stressed cells.
When there are high acutely stressed cells in the lining of the uterus, the lining of the uterus fails to sense the chemical signals from the fertilised egg and it then silences many of the genes involved in allowing the embryo to implant and embed into the uterus.
One of the chemicals needed for this process to take place is Trysin, which is a common enzyme the embryos gives off. If trysin isn’t detected the embryo is not accepted and left to disintegrate and then the cycle is reset once again. The lack of Trysin signal appears to indicate to the endometrium that the quality of the embryo is not very high and initiates a reduction of receptivity to implantation. These findings could help to improve the success rates of IVF, because one of the biggest problems with IVF is getting the embryo to implant
The research team also found that high numbers of Natural Killer cells in the endometrium are not only a sign of high inflammation and acutely stressed uterine cells, but also indicate a insufficient production of steroids, which in turn leads to reduced formation of fats and vitamins that are essential for pregnancy nutrition.
Again, this is exactly what I have been trying to say for years and why when I treat women who are having implantation issues and recurrent miscarriage I look at treating the cause of the issue, rather than masking it.
To treat miscarriage and help with embryo implantation you need to do the following
- Reduce inflammation in the uterine environment and pelvic cavity
- Make sure the pelvis, tubes and uterus have been surgically evaluated properly prior to conception, or assisted reproduction (IVF, IUI, ICSI etc)
- Increase blood flow and nutrients into the uterine lining
- Ensure adequate essential fats and nutrients are given prior to conception
- Reduce stress levels
- Increase protein and reduce inflammatory refined carbohydrates
- Make sure the couple in are optimum health (healthy sperm + healthy eggs=health baby)
- Make sure the man is being treated at the same time the woman is (up to 85% of miscarriage issues are related to chromosomal and DNA factors related to poor quality sperm, which cannot be measured by a normal semen analysis)
We need to stop blaming high NK cells as being the cause of miscarriage and embryos not implanting. We need to look at the real cause, which is inflammation, stressed uterine cells ( due to stress in the person), lack of nutrients and blood flow in the uterus and lifestyle factors that is also leading to increase miscarriage rates and reduced embryo implantation. This is why I have my own range of fertility formulas to assist the uterine environment and help with implantation.
Let’s not forget that faulty sperm and DNA damage and chromosomal issues with sperm are also a big part of miscarriage too. Miscarriage is not just a woman’s issue. To be honest, statistically it is more likely to be on the male side of the equation and often gets overlooked. But that is a whole other post in itself.
This is why I offer a comprehensive fertility program that looks at every aspect of the couple and every aspect of fertility. It is also why I have helped over 12,500 babies into the world. It is about my motto of “No Stone Left Unturned” and treating the cause of people’s issues, not just guessing and trying to treat the symptoms as you go along.
Hopefully in the future this new information will be used to screen women at risk of reproductive failure and help with new treatment options for women suffering recurrent miscarriages or recurrent IVF failure.
If you are having trouble conceiving and want answers to your fertility issues, then maybe it is time to book into my fertility program and get some real answers, real treatment and get the baby you so desperately deserve.
Dr Andrew Orr
-No Stone Left Unturned